PRS4065

Anti-PD-1 (ab1) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• Synonym(e): Anti-CD279, Anti-PDCD1, Anti-Programmed cell death 1
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Konjugat: unconjugated
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: predicted mol wt 32 kDa
• Speziesreaktivität: mouse, human
• Methode(n): immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• UniProt-Hinterlegungsnummer: Q15116
• Versandbedingung: dry ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... PDCD1(5133)

Beschreibung

Allgemeine Beschreibung

PD-1 (programmed death-1) is an immunosuppressive molecule, which is also known as PDCD1 (programmed cell death 1). It is located on chromosome 2q37.3. It is a member of immunoglobulin receptor superfamily.

Immunogen

a 16 amino acid peptide from near the carboxy-terminus of human PD-1.

Biochem./physiol. Wirkung

PD-1 (programmed death-1) gene is sensitive to systemic lupus erythematosus (SLE). Polymorphisms in PD-1 may participate in the growth of EOC (epithelial ovarian cancer). It acts as a negative regulator of T cells. It is also responsible for immune escape mediated by tumor cell.

Verlinkung

The action of this antibody can be blocked using blocking peptide SBP4065.

Physikalische Form

Solution in phosphate buffered saline containing 0.02% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable