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P9544

Sigma-Aldrich

Phosphoglucose-Isomerase aus Kaninchenmuskel

Type XI, lyophilized powder, ≥200 units/mg protein

Synonym(e):

D-Glucose-6-phosphate ketol-isomerase, PGI, Phosphosaccharomutase

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About This Item

CAS-Nummer:
9001-41-6
EC-Nummer:
5.3.1.9 (BRENDA, IUBMB)
EG-Nummer:
232-603-1
MDL-Nummer:
MFCD00131887
UNSPSC-Code:
12352204
NACRES:
NA.54

Biologische Quelle

rabbit muscle

Qualitätsniveau

200

Typ

Type XI

Form

lyophilized powder

Spezifische Aktivität

≥200 units/mg protein

Zusammensetzung

protein, 70-100% biuret

Lagertemp.

−20°C

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Anwendung

Phosphoglucose Isomerase (PGI) is an enzyme crucial for the interconversion of D-glucose 6-phosphate and D-fructose 6-phosphate. PGI is responsible for the second step of glycolysis and is involved in glucogenesis. It is highly conserved in bacteria and eukaryotes. It is used in sugar assays to convert fructose to glucose . Product 9544 is type XI and is from rabbit muscle. It is useful in enzyme systems requiring low sulfate.

Biochem./physiol. Wirkung

Phosphoglucose Isomerase fuctions as an isomerase, neuroleukin, autocrine motility factor, and a differentiation and maturation mediator . It is responsible for the photosynthetic reduction of carbon.

Einheitendefinition

One unit will convert 1.0 μmole of D-fructose 6-phosphate to D-glucose 6-phosphate per min at pH 7.4 at 25 °C.

Physikalische Form

Essentially sulfate-free powder containing citrate buffer salts

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H334

Gefahreneinstufungen

Resp. Sens. 1

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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B K Campbell et al.
Reproduction (Cambridge, England), 140(5), 721-732 (2010-08-19)
Glucose is a critical metabolic fuel in most mammals although many foodstuffs also contain high levels of the monosaccharides, galactose and fructose. The aims of this work were to determine the insulin response to challenges of these sugars (experiment 1)
Yunfeng Peng et al.
Physiologia plantarum, 148(4), 470-480 (2012-10-16)
Nitrogen (N) limitation reduces leaf growth and photosynthetic rates of maize (Zea mays), and constrains photosynthate translocation to developing ears. Additionally, the period from about 1 week before to 2 weeks after silking is critical for establishing the reproductive sink
C J Jeffery et al.
Biochemistry, 39(5), 955-964 (2000-02-02)
The multifunctional protein phosphoglucose isomerase, also known as neuroleukin, autocrine motility factor, and differentiation and maturation mediator, has different roles inside and outside the cell. In the cytoplasm, it catalyzes the second step in glycolysis. Outside the cell, it serves
Natsuko Miura et al.
Eukaryotic cell, 11(8), 1075-1082 (2012-07-04)
Glycolytic enzymes are cytosolic proteins, but they also play important extracellular roles in cell-cell communication and infection. We used Saccharomyces cerevisiae to analyze the secretory pathway of some of these enzymes, including enolase, phosphoglucose isomerase, triose phosphate isomerase, and fructose
Angela Pizzolla et al.
The American journal of pathology, 183(4), 1144-1155 (2013-08-06)
Immunization with human glucose-6-phosphate isomerase (hG6PI) protein or with several of its peptides induces arthritis in DBA/1 mice. We investigated G6PI peptide-induced arthritis in C57BL/10 mice and the effect of oxidative burst on disease. To study the arthritogenicity of G6PI
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