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P6777

Sigma-Aldrich

Phenelzin -sulfat (Salz)

Synonym(e):

Phenelzinhydrogensulfat

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About This Item

Empirische Formel (Hill-System):
C8H12N2 · H2O4S
CAS-Nummer:
156-51-4
Molekulargewicht:
234.27
EG-Nummer:
205-856-0
MDL-Nummer:
MFCD00050687
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24278646
NACRES:
NA.77

Biologische Quelle

synthetic

Qualitätsniveau

200

Assay

≥98% (iodine, titration)

Form

powder

Löslichkeit

water: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow

SMILES String

NNCCC1=CC=CC=C1.OS(=O)(O)=O

InChI

1S/C8H12N2.H2O4S/c9-10-7-6-8-4-2-1-3-5-8;1-5(2,3)4/h1-5,10H,6-7,9H2;(H2,1,2,3,4)

InChIKey

RXBKMJIPNDOHFR-UHFFFAOYSA-N

Angaben zum Gen

human ... MAOA(4128) , MAOB(4129)

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Biochem./physiol. Wirkung

Non-selective MAO-A/B inhibitor.

Leistungsmerkmale und Vorteile

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

H-Sätze

H301

P-Sätze

P301 + P310

Gefahreneinstufungen

Acute Tox. 3 Oral

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Analysenzertifikate (COA)

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Adeline Su-Yin Ngo et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 6(4), 431-434 (2010-07-24)
Phenelzine is an irreversible monoamine oxidase inhibitor (MAOI). Hypertensive reactions after ingestion of tyramine-rich foods such as cheese are well known. However, a review of the available medical literature found no previous reports of myocardial infarction resulting from the ingestion
Travis Musgrave et al.
Brain, behavior, and immunity, 25(8), 1677-1688 (2011-07-05)
Multiple sclerosis (MS) and the animal model, experimental autoimmune encephalomyelitis (EAE), are both accompanied by motor and non-motor symptoms. Pathological changes in the activities of key neurotransmitters likely underlie many of these symptoms. We have previously described disturbances in the
Marco De Giovanni et al.
Immunity, 56(7), 1548-1560 (2023-06-07)
Cryptococcus neoformans is the leading cause of fungal meningitis and is characterized by pathogenic eosinophil accumulation in the context of type-2 inflammation. The chemoattractant receptor GPR35 is expressed by granulocytes and promotes their migration to the inflammatory mediator 5-hydroxyindoleacetic acid
Marco De Giovanni et al.
Science immunology, 9(93), eadj7363-eadj7363 (2024-03-01)
Peyer's patches (PPs) are lymphoid structures situated adjacent to the intestinal epithelium that support B cell responses that give rise to many intestinal IgA-secreting cells. Induction of isotype switching to IgA in PPs requires interactions between B cells and TGFβ-activating
Hideaki Inagaki et al.
Pharmacology, biochemistry, and behavior, 94(4), 575-579 (2009-12-09)
Previously, we demonstrated that an alarm pheromone released from male donor Wistar rats evoked anxiety-related physiological and behavioral responses in recipient rats. Thus, we believe that this pheromone may increase anxiety levels in rats. In the current study, we evaluated
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