P1034

Phenylisothiocyanat

Sigma Grade, 8.36 M, suitable for solid phase protein sequencing analysis, ≥99% (GC), liquid

• Synonym(e): PITC, Phenylsenföl
• Lineare Formel: C₆H₅NCS
• CAS-Nummer: 103-72-0
• Molekulargewicht: 135.19
• UNSPSC Code: 12352118
• NACRES: NA.31
• PubChem Substance ID: 24898144
• EC Number: 203-138-1
• Beilstein/REAXYS Number: 471392
• MDL number: MFCD00004798
• Assay: ≥99% (GC)
• Form: liquid

Eigenschaften

• grade: Sigma Grade
• Quality Level: 100
• assay: ≥99% (GC)
• form: liquid
• concentration: 8.36 M
• refractive index: n20/D 1.6515 (lit.)
• bp: 218 °C (lit.)
• mp: −21 °C (lit.)
• density: 1.132 g/mL at 20 °C (lit.)
• suitability: suitable for solid phase protein sequencing analysis
• storage temp.: 2-8°C
• SMILES string: S=C=Nc1ccccc1
• InChI: 1S/C7H5NS/c9-6-8-7-4-2-1-3-5-7/h1-5H
• InChI key: QKFJKGMPGYROCL-UHFFFAOYSA-N

Beschreibung

General description

Phenyl isothiocyanate belongs to the class of aromatic compounds with isothiocyanate groups. It is typically used as a precolumn derivatization agent for the formation of phenylthiocarbamyl amino acids for their subsequent determination using chromatography techniques.

Application

Derivatisierungsreagens für primäre und sekundäre Amine. Wird gebraucht für die Peptidsequenzierung mittels Edman Abbau und für die Aminosäuren-Analyse mittels HPLC

Phenyl isothiocyanate may be used in the polypeptide and protein sequencing at the subpicomole and subnanomole levels, respectively, by applying automated Edman chemistry followed by the analysis using high-performance liquid chromatography (HPLC) technique.

Packaging

One mL size packaged in flame sealed amber ampules under argon.
Ten mL size packaged in screw cap amber vials under argon.

Sicherheitshinweise

• pictograms: GHS06,GHS08,GHS05
• signalword: Danger
• hcodes: H301,H314,H317,H334
• pcodes: P261 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1
• Lagerklasse: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: 190.4 °F - closed cup
• flash_point_c: 88 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter