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P0022

Sigma-Aldrich

PS48

≥98% (HPLC)

Synonym(e):

5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid

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About This Item

Empirische Formel (Hill-System):
C17H15ClO2
CAS-Nummer:
1180676-32-7
Molekulargewicht:
286.75
MDL-Nummer:
MFCD17215962
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329819977
NACRES:
NA.77

Qualitätsniveau

100

Assay

≥98% (HPLC)

Form

powder

Lagerbedingungen

protect from light

Farbe

white to off-white

Löslichkeit

DMSO: >20 mg/mL

Lagertemp.

2-8°C

SMILES String

OC(=O)\C=C(\CCc1ccc(Cl)cc1)c2ccccc2

InChI

1S/C17H15ClO2/c18-16-10-7-13(8-11-16)6-9-15(12-17(19)20)14-4-2-1-3-5-14/h1-5,7-8,10-12H,6,9H2,(H,19,20)/b15-12-

InChIKey

LLJYFDRQFPQGNY-QINSGFPZSA-N

Biochem./physiol. Wirkung

PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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