O6881

Oxypurinol

≥98% (HPLC)

• Empirische Formel (Hill-System): C₅H₄N₄O₂
• CAS-Nummer: 2465-59-0
• Molekulargewicht: 152.11
• EG-Nummer: 219-570-9
• MDL-Nummer: MFCD00056934
• UNSPSC-Code: 41106305
• PubChem Substanz-ID: 24898041
• NACRES: NA.51

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥98% (HPLC)
• Form: powder
• Löslichkeit: 1 M NaOH: 49.00-51.00 mg/mL, clear to slightly hazy, colorless to yellow (heated NaOH)
• SMILES String: O=C1NC(=O)c2cn[nH]c2N1
• InChI: 1S/C5H4N4O2/c10-4-2-1-6-9-3(2)7-5(11)8-4/h1H,(H3,6,7,8,9,10,11)
• InChIKey: HXNFUBHNUDHIGC-UHFFFAOYSA-N

Beschreibung

Anwendung

Oxypurinol has been used as a xanthine oxidase inhibitor, to evaluate its effects on hepatocellular carcinoma cell proliferation. It has also been used as a xanthine inhibitor to elucidate its contribution in the induction of hpv16 late gene expression.

Oxypurinol, an allopurinol metabolite, is used as an inhibitor to study the specificity and kinetics of of xanthine oxidase(s). Oxypurinol is also used as an anti-inflammatory agent via inhibition of xanthine oxidase.

Biochem./physiol. Wirkung

Oxypurinol has the ability to stimulate osteoblast differentiation and enhance the formation of bone. It is used to treat gout and hyperuricemia. Oxypurinol is considered as a strong antioxidant. It can prevent the actions of xanthine oxidase (XO) in osteoblasts.

An allopurinol metabolite.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves