M9651

Maprotilin -hydrochlorid

>99% (HPLC), powder

• Synonym(e): 9-(γ-Methylaminopropyl)-9,10-dihydro-9,10-ethanoanthracen -hydrochlorid
• Empirische Formel (Hill-System): C₂₀H₂₃N · HCl
• CAS-Nummer: 10347-81-6
• Molekulargewicht: 313.86
• EG-Nummer: 233-758-8
• MDL-Nummer: MFCD00079464
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278576
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 200
• Assay: >99% (HPLC)
• Form: powder
• Farbe: white
• Löslichkeit: H₂O: 50 mg/mL
• Ersteller: Novartis
• SMILES String: Cl.CNCCCC12CCC(c3ccccc13)c4ccccc24
• InChI: 1S/C20H23N.ClH/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20;/h2-5,7-10,15,21H,6,11-14H2,1H3;1H
• InChIKey: NZDMFGKECODQRY-UHFFFAOYSA-N
• Angaben zum Gen: human ... SLC6A2(6530)

Beschreibung

Anwendung

Maprotiline hydrochloride has been used as a inhibitor of norepinephrine uptake to study its effects on arresting L3055 cell proliferation.

Biochem./physiol. Wirkung

Maprotiline is a tetracyclic agent. It possesses inhibitory effects against the uptake of norepinephrine by nerve cells. Maprotiline exhibits anti-depressant and sedative activity.

Leistungsmerkmale und Vorteile

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves