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Merck

M9035

Sigma-Aldrich

IgG1, Kappa from murine myeloma

clone MOPC 31C, purified immunoglobulin, buffered aqueous solution

Synonym(e):

Mouse IgG1-κ

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

unconjugated

Antikörperform

purified immunoglobulin

Klon

MOPC 31C, monoclonal

Assay

≥95% (gel filtration, HPLC)

Form

buffered aqueous solution

Konzentration

≥1 mg/mL

Versandbedingung

dry ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

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Allgemeine Beschreibung

Immunoglobulins (Igs) belongs to the immunoglobulin super-family. IgG is the abundant immunoglobulin in human serum. The four classes of IgG can be IgG1, IgG2, IgG3 and IgG4.
Mammalian immunoglobins contain either lambda or kappa light chains.

Spezifität

Specificity is determined by mouse monoclonal isotyping strips. The purified immunoglobulin preparation is non-reactive with mouse IgA, IgM, IgG2a, IgG2b, or IgG3.

Anwendung

IgG1, Kappa from murine myeloma has been used in:
  • chromatin immunoprecipitation (ChIP)
  • immunofluorescence
  • immunocapture
  • enzyme immunoassay
  • immunohistochemistry

Biochem./physiol. Wirkung

IgG1 is the most abundant and its deficiency results in hypogammaglobulinemia. IgG antibody have enormous therapeutic potential and the Fc region is involved the development of therapeutic antibody.

Physikalische Form

Solution in 0.02 M Tris buffered saline, pH 8.0, containing 0.02% sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Conformational flexibility in the immunoglobulin-like domain of the hepatitis C virus glycoprotein E2
Vasiliauskaite I, et al.
mBio, 8(3), e00382-e00317 (2017)
Expression of HLA-G in malignant mesothelioma and clinically aggressive breast carcinoma
Kleinberg L, et al.
Virchows Archiv, 449(1), 31-39 (2006)
Prevalence of human anti-mouse antibodies (HAMAs) in routine examinations
Koshida S, et al.
Clinica Chimica Acta; International Journal of Clinical Chemistry, 411(5-6), 391-394 (2010)
Margarida Varela Dos Santos et al.
Gynecologic oncology, 176, 76-81 (2023-07-22)
To analyze the expression and prognostic role of L1CAM in tubo-ovarian high-grade serous carcinoma (HGSC). L1CAM protein expression by immunohistochemistry was analyzed in 644 HGSC (413 effusions, 231 surgical specimens). Expression was analyzed for association with clinicopathologic parameters and survival.
Fibronectin-binding protein A of Staphylococcus aureus has multiple, substituting, binding regions that mediate adherence to fibronectin and invasion of endothelial cells
Massey RC, et al.
Cellular Microbiology, 3(12), 839-851 (2001)

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