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Wichtige Dokumente
I4892
Interleukin-7 from mouse
≥97% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, suitable for cell culture
Synonym(e):
IL-7
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About This Item
Empfohlene Produkte
Biologische Quelle
mouse
Qualitätsniveau
Rekombinant
expressed in E. coli
Assay
≥97% (SDS-PAGE)
Form
lyophilized powder
Verpackung
pkg of 5 μg
Lagerbedingungen
avoid repeated freeze/thaw cycles
Methode(n)
cell culture | mammalian: suitable
Verunreinigungen
endotoxin, tested
UniProt-Hinterlegungsnummer
Lagertemp.
−20°C
Angaben zum Gen
mouse ... Il7(16196)
Biochem./physiol. Wirkung
Interleukin-7 is a lymphoid cell growth factor which affects pre-B, pro-B and early T cells. It supports the growth of early B cells and is mitogenic for thymocytes and co-mitogenic with PHA and Con A. IL-7 stimulates the proliferation of CD4/CD8 cells. Human and mouse IL-7 have 60% amino acid sequence identity.
Physikalische Form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 0.25 mg bovine serum albumin.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Cervical thymus mimics the thoracic thymus in supporting T-cell development and exists in a subset of mice and humans. Importantly, it remains unknown whether the cervical thymus can generate T cells that are self-tolerant in the complete absence of signals
Toxicological sciences : an official journal of the Society of Toxicology, 149(1), 31-41 (2015-10-08)
Inhibition of DNA repair and oxidative stress are 2 common mechanisms associated with arsenic-induced genotoxicity. The purpose of this study was to examine mechanisms of genotoxicity induced by environmentally relevant doses of arsenite (As(+3)) in mouse thymus cells. An increase
Vaccine, 32(28), 3509-3516 (2014-05-06)
The flanking amino acids that surround epitopes are critical for effective antigen processing and maintenance of epitope integrity. In the present study, the frequency and characteristics of each amino acid that flanked the peptides generated from the proteasomal degradation of
The Journal of antimicrobial chemotherapy, 70(7), 2108-2120 (2015-04-23)
Therapeutic control of HIV replication reduces the size of the viral reservoir, particularly among central memory CD4+ T cells, and this effect might be accentuated by early treatment. We examined the effect of ART initiated at the time of the
Cancer research, 74(10), 2710-2718 (2014-04-30)
Immunization against self-tumor antigens can induce T-regulatory cells, which inhibit proliferation of type I CD4(+) T-helper (TH1) and CD8(+) cytotoxic T cells. Type I T cells are required for potent antitumor immunity. We questioned whether immunosuppressive epitopes could be identified
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