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I4377
2′,3′-O-Isopropylideneguanosine
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Alle Fotos(2)
About This Item
Empirische Formel (Hill-System):
C13H17N5O5
CAS-Nummer:
Molekulargewicht:
323.30
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41106305
PubChem Substanz-ID:
NACRES:
NA.51
Empfohlene Produkte
Biologische Quelle
synthetic (organic)
Qualitätsniveau
Assay
≥98% (HPLC)
Form
powder
Lagertemp.
−20°C
SMILES String
CC1(C)O[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O1)n3cnc4C(=O)NC(N)=Nc34
InChI
1S/C13H17N5O5/c1-13(2)22-7-5(3-19)21-11(8(7)23-13)18-4-15-6-9(18)16-12(14)17-10(6)20/h4-5,7-8,11,19H,3H2,1-2H3,(H3,14,16,17,20)/t5-,7-,8-,11-/m1/s1
InChIKey
XKPDAYWPKILAMO-IOSLPCCCSA-N
Anwendung
2′,3′-O-Isopropylideneguanosine derivatives may be used as cap analogs.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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H Kasai et al.
Environmental health perspectives, 67, 111-116 (1986-08-01)
Heated glucose is mutagenic to Salmonella typhimurium TA 100 in the absence of S-9 mix. For identifying unknown mutagens in heated glucose (dry solid, 200 degrees C, 20 min), reaction with isopropylideneguanosine (IPG) was followed by isolation and characterization of
G N Bennett et al.
Biochemistry, 14(14), 3152-3158 (1975-07-15)
A number of synthetic methods for the preparation of the 2-O-(alpha-methoxyethyl) derivatives of the 5-diphosphates of adenosine, cytidine, guanosine, and uridine have been studied in order to provide nucleotide substrates that can be applied to the synthesis of specific oligoribonucleotides
H Kasai et al.
IARC scientific publications, 70(70), 413-418 (1986-01-01)
Mutagens present in crude samples such as heated glucose can be detected or identified by means of the adducts formed upon reaction with a fluorescent guanosine derivative (FG) or isopropylideneguanosine (IPG). After the reaction of IPG with heated glucose, two
Anilkumar R Kore et al.
Bioorganic & medicinal chemistry letters, 18(17), 4828-4832 (2008-08-08)
The synthesis and biological evaluation of a new cap analog, which is modified at the C2' and C3' positions of N(7)-methylguanosine is reported. The new cap analog, P(1)-2',3'-isopropylidene, 7-methylguanosine-5'P(3)-guanosine-5'triphosphate was assayed with respect to its effects on efficiency of incorporation
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