I2511

IgG aus Humanserum

reagent grade, ≥95% (HPLC), buffered aqueous solution

• Synonym(e): Human-IgG
• UNSPSC Code: 12352203
• NACRES: NA.46
• MDL number: MFCD00163923
• Conjugate: unconjugated
• Species reactivity: -
• Application: —
• Citations: 90

Eigenschaften

• conjugate: unconjugated
• Quality Segment: 300
• grade: reagent grade
• assay: ≥95% (HPLC)
• form: buffered aqueous solution
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: unmodified

Beschreibung

General description

IgG antibody subtype is the most abundant serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids and provides protection from infections caused by bacteria, fungi and viruses. Maternal IgG is transferred to fetus through the placenta that is vital for immune defence of the neonate against infections
Human IgG is purified from normal human serum by precipitation and gel filtration techniques.

Application

Purified human IgG has been used :-

• as blocking antibody for flow cytometry
• as negative control in chromatin immunoprecipitation assays
• to precipitate IgG in human larynx epidermoid carcinoma cells by immunoprecipitation
• as a standard in enzyme-linked immunosorbent assay

Biochem/physiol Actions

Immunoglobulin G (IgG) regulates the immune responses such as phagocytosis and is also involved in the development of autoimmune diseases. IgG1 regulates complement fixation in mice.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 1