Direkt zum Inhalt
Merck
Alle Fotos(1)

Wichtige Dokumente

Gesamtdokumentation anzeigen

G4256

Sigma-Aldrich

Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast

Type IV, lyophilized powder, 20-60 units/mg protein (modified Warburg-Christian)

Synonym(e):

GALT, UDP glucose:α-D-galactose-1-phosphate uridyltransferase

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise
Alle Fotos(1)

About This Item

CAS-Nummer:
9016-11-9
EC-Nummer:
2.7.7.12 (BRENDA, IUBMB)
MDL-Nummer:
MFCD00131120
UNSPSC-Code:
12352204
NACRES:
NA.54

Typ

Type IV

Qualitätsniveau

300

Form

lyophilized powder

Spezifische Aktivität

20-60 units/mg protein (modified Warburg-Christian)

Zusammensetzung

Protein, 15-35%

Fremdaktivität

6-phosphogluconate dehydrogenase ≤0.5%
UDP glucose pyrophosphorylase and galactokinase ≤0.2%

Lagertemp.

−20°C

Suchen Sie nach ähnlichen Produkten? Aufrufen Leitfaden zum Produktvergleich

Allgemeine Beschreibung

Research area: Cell Signaling

Galactose-1-phosphate uridyltransferase (GALT) is a galactose metabolizing enzyme that facilitates the simultaneous conversion of uridine diphosphoglucose (UDP-glucose) and galactose-1-phosphate (gal-1P) to uridine diphosphogalactose (UDP-galactose) and glucose-1-phosphate. Classic Galactosemia (CG) is an inherited metabolic condition caused by deficiency of GALT activity. GALT gene is mapped to human chromosome 9p13. Deficiency of GALT results in type 1 galactosemia.

Anwendung

Galactose-1-phosphate Uridyltransferase from galactose-adapted yeast has been used to perform enzyme assays.

Einheitendefinition

One unit will form 1.0 μmole of glucose 1-phosphate from UDP-glucose, galactose 1-phosphate and NADP+ per min at pH 8.7 at 25 °C as detected by a coupled system using phosphoglucomutase.

Physikalische Form

Contains buffer salts as citrate and reduced glutathione

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
0000331676
0000331676
0000343978
SLBQ3975V
SLBX0827

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Suche nach COA

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

E Crushell et al.
Journal of inherited metabolic disease, 32(3), 412-415 (2009-05-07)
Classical galactosaemia is relatively common in Ireland due to a high carrier rate of the Q188R GALT mutation. It is screened for using a bacterial inhibition assay (BIA) for free galactose. A Beutler assay on day one of life is
Nir Dai et al.
Plant physiology, 142(1), 294-304 (2006-07-11)
The Cucurbitaceae translocate a significant portion of their photosynthate as raffinose and stachyose, which are galactosyl derivatives of sucrose. These are initially hydrolyzed by alpha-galactosidase to yield free galactose (Gal) and, accordingly, Gal metabolism is an important pathway in Cucurbitaceae
Daniel Lazarevic et al.
Carbohydrate research, 344(12), 1449-1452 (2009-06-30)
All monodeoxygenated galactoses were treated with galactokinase, and for the 2-, 3-, and 4-deoxy compounds, transformation into the corresponding galactopyranosyl phosphates could be observed. In case of the 2-deoxy derivative, further reaction via UDP-2-deoxy-D-lyxo-hexose (UDP-2-deoxygalactose), which was also obtained chemically
Mohamed Jama et al.
The Journal of molecular diagnostics : JMD, 9(5), 618-623 (2007-09-22)
Classic galactosemia is an autosomal recessive inherited error of galactose metabolism. It is caused by lack of galactose-1-phosphate uridyl transferase, an enzyme that is required to metabolize galactose-1-phosphate to uridine diphosphate galactose. The build up of galactose-1-phosphate is toxic at
I Saira Mian et al.
BMC bioinformatics, 7, 305-305 (2006-06-20)
REX1 and REX2 are protein components of the RNA editing complex (the editosome) and function as exouridylylases. The exact roles of REX1 and REX2 in the editosome are unclear and the consequences of the presence of two related proteins are
Alle zugehörigen Dokumente anzeigen

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung.