G1639

D-(+)-Galactosamin -hydrochlorid

BioReagent, suitable for cell culture

• Synonym(e): 2-Amino-2-deoxy-D-galactopyranose -hydrochlorid, D-Chondrosamin -hydrochlorid
• Empirische Formel (Hill-System): C₆H₁₃NO₅ · HCl
• CAS-Nummer: 1772-03-8
• Molekulargewicht: 215.63
• Beilstein: 3697825
• EG-Nummer: 217-198-1
• MDL-Nummer: MFCD00135830
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 24895072
• NACRES: NA.75

Eigenschaften

• Biologische Quelle: fish cartilage (shark)
• Qualitätsniveau: 200
• Produktlinie: BioReagent
• Assay: ≥99%
• Methode(n): cell culture | mammalian: suitable
• Verunreinigungen: Glucosamine, essentially free
• Löslichkeit: water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: Cl.N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)CO
• InChI: 1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1
• InChIKey: CBOJBBMQJBVCMW-NQZVPSPJSA-N

Beschreibung

Anwendung

D-(+)-Galactosamine hydrochloride has been used to:

• induce livery injury
• inflammatory liver injury
• acute liver failure (ALF) in mice

Biochem./physiol. Wirkung

Galactosamine (D-GalN) is synthesized from galactose and is potential hepatotoxic agent. D-GalN in combination with lipopolysaccharide leads to the development of lethal liver injury and hepatic failure. It sensitizes cells to the toxic effects of the cytokine in particular the tumor necrosis factor(TNF).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)