F9677

Felodipin

solid

• Synonym(e): 4-(2,3-Dichlorphenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridincarbonsäure-ethyl-methylester, Plendil
• Empirische Formel (Hill-System): C₁₈H₁₉NO₄Cl₂
• CAS-Nummer: 72509-76-3
• Molekulargewicht: 384.25
• MDL-Nummer: MFCD00868316
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 24278449
• NACRES: NA.77

Eigenschaften

• Form: solid
• Qualitätsniveau: 200
• Löslichkeit: DMSO: 20 mg/mL; H₂O: insoluble
• Ersteller: AstraZeneca
• SMILES String: CCOC(=O)C1=C(C)NC(C)=C(C1c2cccc(Cl)c2Cl)C(=O)OC
• InChI: 1S/C18H19Cl2NO4/c1-5-25-18(23)14-10(3)21-9(2)13(17(22)24-4)15(14)11-7-6-8-12(19)16(11)20/h6-8,15,21H,5H2,1-4H3
• InChIKey: RZTAMFZIAATZDJ-UHFFFAOYSA-N
• Angaben zum Gen: human ... CACNA1C(775) , CACNA1D(776) , CACNA1F(778) , CACNA1S(779) , CACNA2D1(781) , NR3C2(4306)

Beschreibung

Allgemeine Beschreibung

Felodipine is a dihydropyridine derivative. It has diuretic properties. Felodipine has high vascular selectivity. It is used to treat hypertension. Felodipine regulates chronic stable angina.

Biochem./physiol. Wirkung

L-type calcium channel blocker

Leistungsmerkmale und Vorteile

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H302,H361d,H373,H410
• P-Sätze: P202 - P260 - P264 - P273 - P301 + P312 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Repr. 2 - STOT RE 2 Inhalation
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves