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D8517

Sigma-Aldrich

Eisen-Dextran

95-105 mg/mL (Iron content), solution

Synonym(e):

Ferric hydroxide dextran complex

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About This Item

CAS-Nummer:
9004-66-4
MDL-Nummer:
MFCD00081553
UNSPSC-Code:
12352201
NACRES:
NA.25

Biologische Quelle

synthetic

Qualitätsniveau

200

Sterilität

aseptically filled

Assay

95-105 mg/mL (Iron content)

Form

solution

Enthält

0.5% phenol as preservative

Zusammensetzung

Iron, ~100 mg/mL

Farbe

brown

Nützlicher pH-Bereich

4 - 6.5

Lagertemp.

room temp

SMILES String

[Fe].[S](=O)(=O)(O)O

InChI

1S/Fe.H2O4S/c;1-5(2,3)4/h;(H2,1,2,3,4)

InChIKey

MVZXTUSAYBWAAM-UHFFFAOYSA-N

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Anwendung

Iron-Dextran (ferric hydroxide dextran complex) may be used as an intravenous iron delivery preparation. Iron-Dextran may be used to induce iron-overload to study its effects and preventative measures.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.

Piktogramme

Health hazardExclamation mark
GHS08,GHS07

Signalwort

Danger

H-Sätze

H317,H350

Gefahreneinstufungen

Carc. 1B - Skin Sens. 1

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Markus R Jahn et al.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 78(3), 480-491 (2011-03-29)
The treatment of iron deficiency anemia with polynuclear iron formulations is an established therapy in patients with chronic kidney disease but also in other disease areas like gastroenterology, cardiology, oncology, pre/post operatively and obstetrics' and gynecology. Parenteral iron formulations represent
D L Burns et al.
Nutrition (Burbank, Los Angeles County, Calif.), 11(2), 163-168 (1995-03-01)
Iron dextran was introduced more than 30 yr ago for the parenteral treatment of iron deficiency anemia that is refractory to oral therapy. Iron dextran is a preparation of ferric hydroxide complexed with a low molecular weight fraction of dextran.
V J Kumpf et al.
DICP : the annals of pharmacotherapy, 24(2), 162-166 (1990-02-01)
Parenteral iron therapy is indicated in patients with iron-deficiency anemia associated with conditions that interfere with the ingestion or absorption of oral iron. Replacement doses of iron required to replenish iron stores are based on body weight and the observed
Priya Prakash Karmali et al.
Molecular pharmaceutics, 9(3), 539-545 (2012-01-17)
Premature recognition and clearance of nanoparticulate imaging and therapeutic agents by macrophages in the tissues can dramatically reduce both the nanoparticle half-life and delivery to the diseased tissue. Grafting nanoparticles with hydrogels prevents nanoparticulate recognition by liver and spleen macrophages
I V Alenkina et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 100, 88-93 (2012-04-03)
Application of Mössbauer spectroscopy with a high velocity resolution (4096 channels) for comparative analysis of iron cores in a human liver ferritin and its pharmaceutically important models Imferon, Maltofer(®) and Ferrum Lek as well as in iron storage proteins in
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