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Merck

C5020

Sigma-Aldrich

Cefazolin Natriumsalz

89.1-110.1%

Synonym(e):

Cefazoline sodium, Monosodium cefazolin

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About This Item

Empirische Formel (Hill-System):
C14H13N8NaO4S3
CAS-Nummer:
Molekulargewicht:
476.49
Beilstein:
3585038
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
51282532
PubChem Substanz-ID:
NACRES:
NA.76

Qualitätsniveau

Assay

89.1-110.1%

Form

powder

Wirkungsspektrum von Antibiotika

Gram-negative bacteria
Gram-positive bacteria

Wirkungsweise

cell wall synthesis | interferes

Lagertemp.

2-8°C

SMILES String

[Na+].Cc1nnc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C([O-])=O)s1

InChI

1S/C14H14N8O4S3.Na/c1-6-17-18-14(29-6)28-4-7-3-27-12-9(11(24)22(12)10(7)13(25)26)16-8(23)2-21-5-15-19-20-21;/h5,9,12H,2-4H2,1H3,(H,16,23)(H,25,26);/q;+1/p-1/t9-,12-;/m1./s1

InChIKey

FLKYBGKDCCEQQM-WYUVZMMLSA-M

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Allgemeine Beschreibung

Chemical structure: ß-lactam

Biochem./physiol. Wirkung

Used to study the effect of expression, binding and inhibition of penicillin-binding proteins, especially PBP2 and PBP4 on bacterial cell wall mucopeptide synthesis.

Angaben zur Herstellung

Freely soluble in water, very slightly soluble in chloroform and ethanol.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Piktogramme

Health hazard

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Resp. Sens. 1 - Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves


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Kevin E Chan et al.
Journal of the American Society of Nephrology : JASN, 23(9), 1551-1559 (2012-08-21)
Staphylococcus bacteremia is a common and life-threatening medical emergency, but it is treatable with appropriate antibiotic therapy. To identify opportunities that may reduce morbidity and mortality associated with S. aureus, we analyzed data from 293,094 chronic hemodialysis outpatients to characterize
Keita Kamikura et al.
Journal of materials science. Materials in medicine, 28(9), 132-132 (2017-07-27)
It has been experimentally proven that orally ingested collagen-derived tripeptides (Ctp) are quickly absorbed in the body and effectively promote the regeneration of connective tissues including bone and skin. Ctp are capable to activate osteoblasts and fibroblasts, which eventually promotes
Martin Andreas et al.
The Annals of thoracic surgery, 95(4), 1323-1329 (2013-03-07)
Internal mammary artery (IMA) harvesting for coronary artery bypass grafting (CABG) influences tissue perfusion and represents a risk factor for deep sternal wound infection (DSWI). Cephalosporins are routinely administered for prophylaxis during cardiac operations to decrease perioperative wound infections. We
Colleen K Cagno et al.
American family physician, 86(1), 59-65 (2012-09-12)
Group B streptococcus is the leading cause of early-onset neonatal sepsis in the United States. Universal screening is recommended for pregnant women at 35 to 37 weeks' gestation. The Centers for Disease Control and Prevention recently updated its guideline for
Jabeen Noore et al.
Antimicrobial agents and chemotherapy, 57(3), 1283-1290 (2013-01-01)
The increasing resistance of bacteria to conventional antibiotics and the challenges posed by intracellular bacteria, which may be responsible for chronic and recurrent infections, have driven the need for advanced antimicrobial drugs for effective elimination of both extra- and intracellular

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