C3788

Dermatansulfat Natriumsalz

from Porcine intestinal mucosa, ≥90%, lyophilized powder

• Synonym(e): β-Heparin, Chondroitin-Sulfat B Natriumsalz
• CAS-Nummer: 54328-33-5
• MDL-Nummer: MFCD00151683
• UNSPSC-Code: 12352201
• NACRES: NA.25

Eigenschaften

• Biologische Quelle: Porcine intestinal mucosa
• Qualitätsniveau: 200
• Assay: ≥90%
• Form: lyophilized powder
• Verunreinigungen: ≤20% water (Karl Fischer)
• Farbe: white
• Löslichkeit: H₂O: 5 mg/mL, clear, colorless
• Kationenspuren: Na: 7.0-11.5%
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

Chondroitin, a glucosaminoglycan (GAG), is a polysaccharide chain of alternating units of N-acetylgalactosamine (GalNAc) and glucuronic acid (GlcA) that can be sulfated on the either or both GalNAc and GlcA units. Chondroitin and its sulfates are frequently attached to proteins to form proteoglycans. Chondroitin sulfate B (Dermatam sulfate) is a component of proteoglycans such as decorin, biglycan and versican. Chondroitin sulfate B is used to study β peptide (1-42) cytotoxicity.

Anwendung

Chondroitin sulfate B may be used to study its roles as a biomolecule receptor, mediator of cell signaling and cell binding molecule. It may be used to compare its properties to those of chondroitin sulfate A and chondroitin sulfate C. Chondroitin sulfate B is used to study β peptide(1-42) cytotoxicity.

Biochem./physiol. Wirkung

As a large, negatively charged, hydrophilic molecule that is too inflexible to fold into a compact globular structure, chondroitin sulfate molecules form porous hydrated gels, providing mechanical support to tissue and allowing rapid diffusion of water-soluble molecules and migration of cells.

Komponenten

Chondroitin Sulfate B is an acidic mucopolysaccharide found in cartilage, skin, cornea, and umbilical cord. It is composed of alternating N-acetylgalactosamine, L-iduronic acid, and sulfate residues in equimolar quantities where carbon 4 of the N-acetylgalactosamines is sulfated.

Vorsicht

Store this product at 2-8°C.

Angaben zur Herstellung

This product is soluble in water at 100 mg/mL.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)