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B5057

Sigma-Aldrich

7-Benzyloxy-4-trifluoromethylcoumarin

≥99% (HPLC), solid

Synonym(e):

7-BFC

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About This Item

Empirische Formel (Hill-System):
C17H11F3O3
Molekulargewicht:
320.26
MDL-Nummer:
MFCD01564466
UNSPSC-Code:
12161501
PubChem Substanz-ID:
24891807
NACRES:
NA.47

product name

7-Benzyloxy-4-trifluoromethylcoumarin, ≥99% (HPLC), solid

Qualitätsniveau

100

Assay

≥99% (HPLC)

Form

solid

Lagertemp.

−20°C

SMILES String

FC(F)(F)C1=CC(=O)Oc2cc(OCc3ccccc3)ccc12

InChI

1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2

InChIKey

WVKLERKKJXUPIK-UHFFFAOYSA-N

Angaben zum Gen

rat ... Maoa(29253) , Maob(25750)

Anwendung

7-Benzyloxy-4-trifluoromethylcoumarin has been used:

  • in the SBAD2-3x-AAGLY hepatocyte-like cell (HLC) functional assay to measure the cytochrome P450 3A4 (CYP3A4)-dependent activity
  • in O-dealkylation reaction to determine the activity of CYP3A
  • to measure the activity of CYP3A-mediated 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase activity (BFCOD)

Biochem./physiol. Wirkung

Metabolized primarily by cytochrome P450 isozymes CYP1A2 and CYP3A4.

Rechtliche Hinweise

Supplied by Gentest Corp., U.S. Patent Nos. 6,207,404.

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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