01897

Adenosin-5′-diphosphat Dinatriumsalz

≥90%

• Synonym(e): 5′-ADP-Na₂
• Empirische Formel (Hill-System): C₁₀H₁₃N₅Na₂O₁₀P₂
• CAS-Nummer: 16178-48-6
• Molekulargewicht: 471.16
• Beilstein: 7563620
• EG-Nummer: 240-314-7
• MDL-Nummer: MFCD00066635
• UNSPSC-Code: 41106305
• eCl@ss: 32160414
• PubChem Substanz-ID: 329747370
• NACRES: NA.51

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥90%
• Form: powder or crystals
• Optische Aktivität: [α]20/D −29.6±1°, c = 0.5% in 0.5 M Na₂HPO₄
• Verunreinigungen: ≤10% water
• Lagertemp.: −20°C
• SMILES String: [Na+].[Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](COP([O-])(=O)OP(O)([O-])=O)[C@@H](O)[C@H]3O
• InChI: 1S/C10H15N5O10P2.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/p-2/t4-,6-,7-,10-;;/m1../s1
• InChIKey: ORKSTPSQHZNDSC-IDIVVRGQSA-L

Beschreibung

Anwendung

Adenosine 5′-diphosphate disodium salt has been used as a purinergic G protein-coupled receptor P2Y12 agonistin platelet activation tests in blood samples.

Biochem./physiol. Wirkung

Adenosine 5′-diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism via its conversion into ATP by ATP synthases. ADP affects platelet activation through its interaction with purinergic receptors P2Y₁ and P2Y₁₂. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)