366927

Chloroform

suitable for HPLC, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

• Synonym(e): Methylidyntrichlorid, Trichlormethan
• Empirische Formel (Hill-System): CHCl₃
• CAS-Nummer: 67-66-3
• Molekulargewicht: 119.38
• Beilstein: 1731042
• MDL-Nummer: MFCD00000826
• UNSPSC-Code: 12190000
• PubChem Substanz-ID: 329755457
• NACRES: NA.04

Eigenschaften

• Dampfdichte: 4.1 (vs air)
• Qualitätsniveau: 100
• Dampfdruck: 160 mmHg ( 20 °C)
• Assay: ≥99.8%
• Form: liquid
• Aufgereinigt durch: glass distillation
• Enthält: 0.5-1.0% ethanol as stabilizer
• Methode(n): HPLC: suitable
• Verunreinigungen: Acetone and aldehyde, passes test; Acid and chloride, passes test; Free chlorine (Cl), passes test; H₂SO₄, passes test (darkened); ≤0.01% water
• Abdampfrückstand: <0.0003%
• Farbe: APHA: ≤10
• Brechungsindex: n20/D 1.445 (lit.)
• bp: 60.5-61.5 °C (lit.)
• mp (Schmelzpunkt): −63 °C (lit.)
• Dichte: 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
• Kationenspuren: Pb: ≤0.05 ppm
• λ: H₂O reference
• UV-Absorption: λ: 245 nm A_max: 1.00; λ: 255 nm A_max: 0.15; λ: 260 nm A_max: 0.15; λ: 270 nm A_max: 0.02; λ: 290 nm A_max: 0.01; λ: 400 nm A_max: 0.01
• Eignung: passes test for HPLC
• Lagertemp.: room temp
• SMILES String: ClC(Cl)Cl
• InChI: 1S/CHCl3/c2-1(3)4/h1H
• InChIKey: HEDRZPFGACZZDS-UHFFFAOYSA-N

Beschreibung

Anwendung

• Novel Approaches for the Analysis and Isolation of Benzylisoquinoline Alkaloids in Chelidonium majus.: This study presents innovative methodologies using chloroform in the extraction and analysis processes, highlighting advances in alkaloid chemistry (Ganzera et al., 2024).


• Antioxidant, anti-amylase, anti-lipase, and efficiency of Satureja fatty acid on the anti-inflammatory parameters in lipopolysaccharide-stimulated macrophage through Nrf2/NF-kB/NADH oxidase pathway.: Although primarily focused on biological assays, this paper includes essential methodologies employing chloroform for the extraction and purification of biochemical compounds (Saharkhiz MJ et al., 2024).


• Recent additions and access to a multidimensional lipidomic database containing liquid chromatography, ion mobility spectrometry, and tandem mass spectrometry information.: Chloroform is utilized as a key solvent in the extraction and analysis processes within lipidomics, demonstrating its critical role in modern analytical techniques (Baker ES et al., 2024).


• Preparation and optimization of dummy molecularly imprinted polymer-based solid-phase extraction system for selective enrichment of p-toluene sulfonate esters genotoxic impurities.: The study includes the use of chloroform in the preparation of polymers for advanced chromatographic applications, illustrating its versatility in analytical methodologies (Shan G et al., 2024).

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Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H302,H315,H319,H331,H336,H351,H361d,H372
• P-Sätze: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Zielorgane: Central nervous system, Liver,Kidney
• Lagerklassenschlüssel: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): does not flash
• Flammpunkt (°C): does not flash