PHR1594

Methacyclin-Hydrochlorid

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Methacyclin -hydrochlorid, 6-Demethyl-6-deoxy-6-methylenoxytetracyclin-monohydrochlorid
• Empirische Formel (Hill-System): C₂₂H₂₂N₂O₈ · HCl
• CAS-Nummer: 3963-95-9
• Molekulargewicht: 478.88
• Beilstein: 5470951
• EG-Nummer: 223-568-3
• MDL-Nummer: MFCD04972012
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823498
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to BP 911; traceable to USP 1397006
• API-Familie: methacycline
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 1 g
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: -10 to -25°C
• SMILES String: Cl[H].[H][C@@]12[C@@H](O)[C@]3([H])C(=C)c4cccc(O)c4C(=O)C3=C(O)[C@]1(O)C(=O)C(C(N)=O)=C(O)[C@H]2N(C)C
• InChI: 1S/C22H22N2O8.ClH/c1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;/h4-6,10,14-15,17,25,27-29,32H,1H2,2-3H3,(H2,23,31);1H/t10-,14-,15+,17+,22+;/m1./s1
• InChIKey: VZQARNDJLLWXGL-CCHMMTNSSA-N

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Methacycline hydrochloride is one of the tetracycline antibiotics effective against a broad-spectrum of Gram-positive and Gram-negative bacteria. It is formed as an intermediate during the preparation of oxytetracycline. Its antibacterial activity is higher than that of tetracycline and oxytetracycline. It finds applications in human and veterinary medications as well as feed additives.

Anwendung

Methacycline hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography and electroanalytical techniques.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC2077 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable