PHR1533

Cholesterin

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Cholesterin, 3β-Hydroxy-5-cholesten, 5-Cholesten-3β-ol
• Empirische Formel (Hill-System): C₂₇H₄₆O
• CAS-Nummer: 57-88-5
• Molekulargewicht: 386.65
• Beilstein: 1915888
• EG-Nummer: 200-353-2
• MDL-Nummer: MFCD00003646
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329823445
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. C2155000; traceable to USP 1131960
• API-Familie: cholesterol
• Form: powder
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 500 mg
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• bp: 360 °C (lit.)
• mp (Schmelzpunkt): 147-149 °C (lit.)
• Löslichkeit: water: soluble 0.00003 g/L at 20 °C
• Dichte: 1.067 g/mL at 25 °C (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: -10 to -25°C
• SMILES String: CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
• InChI: 1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
• InChIKey: HVYWMOMLDIMFJA-DPAQBDIFSA-N

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Cholesterol is a waxy material that belongs to the class of sterol-lipids found naturally in foods from animal sources, such as egg yolks, meat, and cheese. It serves as a precursor for the biosynthesis of steroid hormones, bile acid and vitamin D.

Anwendung

Cholesterol may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and food products by gas chromatography, or by high performance liquid chromatography.

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Hauptbestandteil biologischer Membranen; ca. 25% des gesamten Lipids im Gehirn ist Cholesterin.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC0249 in the slot below. This is an example certificate only and may not be the lot that you receive.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable