P2759

Phloxin B

Powder

• Synonym(e): 2′,4′,5′,7′-Tetrabrom-4,5,6,7-tetrachlor-fluorescein Dinatriumsalz, Cyanosin, D&C;Red No. 28, Eosin 10B, Eosin S extra bläulich, Säurerot 92
• Empirische Formel (Hill-System): C₂₀H₂Br₄Cl₄Na₂O₅
• CAS-Nummer: 18472-87-2
• Molekulargewicht: 829.63
• Farbindexnummer: 45410
• Beilstein: 3887100
• EG-Nummer: 242-355-6
• MDL-Nummer: MFCD00070627
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24898359
• NACRES: NA.47

Eigenschaften

• product name: Phloxin B, antibacterial fluorescent dye
• Qualitätsniveau: 200
• Form: powder
• Methode(n): microbe id | staining: suitable
• Farbe: dark red
• Löslichkeit: water: 1 mg/mL, clear, red
• εmax: 1150-1300 at 546-550 nm in 50% ethanol
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: [Na+].[Na+].[O-]c1c(Br)cc2c(Oc3c(Br)c([O-])c(Br)cc3C24OC(=O)c5c(Cl)c(Cl)c(Cl)c(Cl)c45)c1Br
• InChI: 1S/C20H4Br4Cl4O5.2Na/c21-5-1-3-17(9(23)15(5)29)32-18-4(2-6(22)16(30)10(18)24)20(3)8-7(19(31)33-20)11(25)13(27)14(28)12(8)26;;/h1-2,29-30H;;/q;2*+1/p-2
• InChIKey: OOYIOIOOWUGAHD-UHFFFAOYSA-L

Beschreibung

Anwendung

Phloxine B has been used to trace the uptake of double stranded RNA by green peach aphids. It has also been used to stain yeast strains.

Biochem./physiol. Wirkung

Phloxine B has been demonstrated as an alternative to Gram staining. It was found to inhibit the growth of methicillin-resistant Staphylococcus aureus. Phloxine B stimulated and inhibited the channel activity of wild-type cystic fibrosis transmembrane conductance regulator (CFTR). It has antibacterial properties. Phloxine B staining can be used to distinguish between gram-positive and gram-negative bacteria.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)