N0600000

Nicotinamid

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): Niacinamid, Nicotinsäureamid, Pyridin-3-carbonsäureamid, Vitamin B₃, Vitamin PP
• Empirische Formel (Hill-System): C₆H₆N₂O
• CAS-Nummer: 98-92-0
• Molekulargewicht: 122.12
• Beilstein: 383619
• MDL-Nummer: MFCD00006395
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329818447
• NACRES: NA.24

Eigenschaften

• Biologische Quelle: synthetic
• Qualität: pharmaceutical primary standard
• API-Familie: nicotinamide
• Form: solid
• Hersteller/Markenname: EDQM
• Methode(n): gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• mp (Schmelzpunkt): 128-131 °C (lit.)
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: NC(=O)c1cccnc1
• InChI: 1S/C6H6N2O/c7-6(9)5-2-1-3-8-4-5/h1-4H,(H2,7,9)
• InChIKey: DFPAKSUCGFBDDF-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.
Nicotinamide belongs to the group of water-soluble B vitamins. It is generally formed from nicotinic acid (vitamin B₃). It is available in food products and is utilized for the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It is also known for its anti-inflammatory activity.

Anwendung

Nicotinamide can be used as an EP reference standard for the quantification of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis.

Biochem./physiol. Wirkung

Nicotinamid ist ein Amid-Derivat von Vitamin B3 und ein PARP-Inhibitor.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Kann Verkaufsbeschränkungen unterliegen.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H319
• P-Sätze: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Gefahreneinstufungen: Eye Irrit. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): 302.0 °F - closed cup
• Flammpunkt (°C): 150 °C - closed cup