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Merck

B0490000

Benzaron

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

(2-Ethylbenzofuran-3-yl)(4-hydroxyphenyl)-methanon, NSC 82134

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About This Item

Empirische Formel (Hill-System):
C17H14O3
CAS-Nummer:
Molekulargewicht:
266.29
MDL-Nummer:
UNSPSC-Code:
41116107
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

benzarone

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

[o]1c2c(c(c1CC)C(=O)c3ccc(cc3)O)cccc2

InChI

1S/C17H14O3/c1-2-14-16(13-5-3-4-6-15(13)20-14)17(19)11-7-9-12(18)10-8-11/h3-10,18H,2H2,1H3

InChIKey

RFRXIWQYSOIBDI-UHFFFAOYSA-N

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Benzarone EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Sonstige Hinweise

Sales restrictions may apply.

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

H Köstering et al.
Arzneimittel-Forschung, 35(8), 1303-1306 (1985-01-01)
The analyses on hemostaseological variables are recorded in connection with blood tests in the course of a double-blind study in 41 patients suffering from chronic venous insufficiency of higher degrees of severity. They were treated in addition to compression measures
Priska Kaufmann et al.
Hepatology (Baltimore, Md.), 41(4), 925-935 (2005-03-31)
Treatment with benzarone or benzbromarone can be associated with hepatic injury. Both drugs share structural similarities with amiodarone, a well-known mitochondrial toxin. Therefore, we investigated the hepatotoxicity of benzarone and benzbromarone as well as the analogues benzofuran and 2-butylbenzofuran. In
H E Knehr et al.
Arzneimittel-Forschung, 33(2), 211-214 (1983-01-01)
The influence of 2-ethyl-3-(4-hydroxy-benzoyl)-benzofurane (benzarone, Fragivic) on the energy metabolism of the wall of the rabbit common carotid artery and the rat portal vein was investigated by measuring the oxygen consumption of in vitro incubated vessel segments. Benzarone increased the
A Schmidt et al.
Arzneimittel-Forschung, 32(8), 810-815 (1982-01-01)
Rats of BD X strain and SHR/NIH Montreal Ingelheim strain (genetic hypertension) received a diet containing 3.9% cholesterol or 3.7% cholesterol plus 0.6% benzarone, respectively, and libitum for 5 or 9 months. The following chemical and ultrastructural results were obtained.
Effect of anti-inflammatory agents on the glycosaminoglycan metabolism in cultured human synovial cells.
K Kleesiek et al.
Rheumatology international, 2(4), 167-174 (1982-01-01)

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