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Merck

91842

Supelco

Naringin

analytical standard

Synonym(e):

4′,5,7-Trihydroxyflavanon-7-rhamnoglucosid, Naringenin-7-neohesperidosid, Naringenin-7-rhamnosidoglucosid, Naringosid

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About This Item

Empirische Formel (Hill-System):
C27H32O14
CAS-Nummer:
Molekulargewicht:
580.53
Beilstein:
102012
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
NACRES:
NA.24

Qualitätsniveau

Qualität

analytical standard

Assay

≥95.0% (HPLC)

Optische Aktivität

[α]/D -80±10°, c = 1 in ethanol

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

Format

neat

SMILES String

C[C@@H]1O[C@@H](O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]2Oc3cc(O)c4C(=O)CC(Oc4c3)c5ccc(O)cc5)[C@H](O)[C@H](O)[C@H]1O

InChI

1S/C27H32O14/c1-10-20(32)22(34)24(36)26(37-10)41-25-23(35)21(33)18(9-28)40-27(25)38-13-6-14(30)19-15(31)8-16(39-17(19)7-13)11-2-4-12(29)5-3-11/h2-7,10,16,18,20-30,32-36H,8-9H2,1H3/t10-,16?,18+,20-,21+,22+,23-,24+,25+,26-,27+/m0/s1

InChIKey

DFPMSGMNTNDNHN-JJLSSNRUSA-N

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Allgemeine Beschreibung

Naringin is a naturally occurring flavone glycoside, which may possess many pharmacological properties like anti-inflammatory, anti-oxidant and anti-apoptotic activity. It is widely found in fruits like grapes and oranges.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Naringin, a flavanoid in grapefruit and other citrus fruits, potently inhibits intestinal organic anion-transporting polypeptide 1A2 (OATP1A2). Grapefruit juice thereby reduces bioavailability of many pharmacological agents taken at the same time.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Kunden haben sich ebenfalls angesehen

Naringin ameliorates diabetic nephropathy by inhibiting NADPH oxidase 4
Zhang J, et al.
European Journal of Pharmacology, 804, 1-6 (2017)
Therapeutic effects of silymarin and naringin on methotrexate?induced nephrotoxicity in rats: Biochemical evaluation of anti?inflammatory, antiapoptotic, and antiautophagic properties
Kandemir MF, et al.
Journal of Food Biochemistry, 41 (2017)
Ayman M Mahmoud et al.
Journal of diabetes and its complications, 26(6), 483-490 (2012-07-20)
Abnormal regulation of glucose and impaired carbohydrate utilization that result from a defective or deficient insulin are the key pathogenic events in type 2 diabetes mellitus (T2DM). The present study was hypothesized to investigate the beneficial effects of hesperidin and
Yi-Chu Nie et al.
Journal of medicinal food, 15(10), 894-900 (2012-09-19)
Naringin, a well-known flavanone glycoside of grapefruit and citrus fruits, was found to be as an effective anti-inflammatory compound in our previous lipopolysaccharide-induced acute lung injury mouse model via blockading activity of nuclear factor κB. The current study sought to
Jiukai Zhang et al.
Food chemistry, 135(3), 1471-1478 (2012-09-08)
Huyou (Citrus changshanensis) is rich in naringin and neohesperidin, which are natural flavanone glycosides with a range of biological activities. Among the different fruit parts, i.e. flavedo, albedo, segment membrane (SM), and juice sacs (JS), albedo showed the highest contents

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