4-Methyl-5-thiazolethanol

Name: 4-Methyl-5-thiazolethanol
Brand: SIAL

analytical standard

Synonym(e):

5-(2-Hydroxyethyl)-4-methyl-thiazol, Sulfurol

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Empirische Formel (Hill-System):

C₆H₉NOS

CAS-Nummer:

137-00-8

Molekulargewicht:

143.21

UNSPSC Code:

85151701

NACRES:

NA.24

PubChem Substance ID:

329759444

EC Number:

205-272-6

Beilstein/REAXYS Number:

114249

MDL number:

MFCD00005339

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Produktname

4-Methyl-5-thiazolethanol, analytical standard

InChI key

BKAWJIRCKVUVED-UHFFFAOYSA-N

InChI

1S/C6H9NOS/c1-5-6(2-3-8)9-4-7-5/h4,8H,2-3H2,1H3

SMILES string

Cc1ncsc1CCO

grade

analytical standard

assay

≥98.0% (GC)

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

impurities

≤0.5% water

refractive index

n20/D 1.550 (lit.)
n20/D 1.550±0.001

bp

135 °C/7 mmHg (lit.)

density

1.196 g/mL at 25 °C (lit.)

application(s)

cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care

format

neat

Quality Level

100

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Dieser Artikel	91307	43236	80345
Supelco 61352 4-Methyl-5-thiazolethanol	Supelco 91307 5-Methylfurfural	Supelco 43236 2-Ethyl-3,5(6)-dimethylpyrazin, Isomerenmischung	Supelco 80345 Tyramin
technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable	technique(s) HPLC: suitable, gas chromatography (GC): suitable
grade analytical standard	grade analytical standard	grade analytical standard	grade analytical standard
application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care	application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care	application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care	application(s) cleaning products cosmetics flavors and fragrances food and beverages personal care
format neat	format neat	format neat	format neat
assay ≥98.0% (GC)	assay ≥98.5% (GC)	assay ≥98.0% (GC)	assay ≥98.5% (GC), 98.0-102.0% (wt., NT)
shelf life limited shelf life, expiry date on the label	shelf life limited shelf life, expiry date on the label	shelf life limited shelf life, expiry date on the label	shelf life limited shelf life, expiry date on the label

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

pictograms

GHS07

signalword

Warning

hcodes

H315,H319,H335

pcodes

P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

10 - Combustible liquids

wgk

WGK 2

flash_point_f

233.6 °F - closed cup

flash_point_c

112 °C - closed cup

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Biosynthesis of thiamin thiazole: determination of the regiochemistry of the S/O acyl shift by using 1,4-dideoxy-D-xylulose-5-phosphate.

Abhishek Chatterjee et al.

Angewandte Chemie (International ed. in English), 45(21), 3507-3510 (2006-04-21)

[Effect of thiamine and its derivatives on acetylcholinesterase activity of the blood and brain of albino mice].

S A Petrov et al.

Ukrainskii biokhimicheskii zhurnal (1978), 59(3), 76-79 (1987-05-01)

Thiamine, thiaminepyrophosphate and 4-methyl-5-beta-oxyethylthiazole are studied for their effect on the acetylcholinesterase activity in the brain, blood plasma and cells. The activity of acetylcholinesterase in blood cells is shown to be inhibited most of all by thiamine and thiazole. Acetylcholinesterase

Amiloride toxicity in the fission yeast Schizosaccharomyces pombe is released by thiamine and mutations in the thiamine-repressible gene car1.

C Niederberger et al.

Gene, 171(1), 119-122 (1996-05-24)

Amiloride (Am) inhibits growth in the fission yeast Schizosaccharomyces pombe. We show that the toxic effect of this drug is relieved by low concentrations of thiamine (Th) and that the pyrimidine moiety of the Th molecule is responsible for growth

Characterization of thiI, a new gene involved in thiazole biosynthesis in Salmonella typhimurium.

E Webb et al.

Journal of bacteriology, 179(13), 4399-4402 (1997-07-01)

Thiamine pyrophosphate (TPP) is a required cofactor in Salmonella typhimurium that is generated de novo by the condensation of 4-amino-5-hydroxymethyl pyrimidine (HMP) pyrophosphate and 4-methyl-5-(beta-hydroxyethyl)-thiazole (THZ) monophosphate. The THZ and HMP moieties are independently synthesized, and labeling studies have demonstrated

[Comparative studies of 35S-hemineurine and 35S-thiamine distribution and binding by proteins in the neural structures of the rat brain].

L B Filippova et al.

Voprosy meditsinskoi khimii, 26(5), 643-646 (1980-09-01)

35S-Hemineurine penetrated across the blood-brain barrier more rapidly than 35S-thiamin within the first 30 min after intravenous administration. Within 24 hrs content of 35S-thiamin in the neurones exceeded by 34% its concentration in glia and by 200% -- in myelin

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4-Methyl-5-thiazolethanol

analytical standard

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Produktname

InChI key

InChI

SMILES string

grade

assay

shelf life

technique(s)

impurities

refractive index

bp

density

application(s)

format

Quality Level

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Beschreibung

Application

Packaging

Sicherheitshinweise

pictograms

signalword

hcodes

pcodes

Hazard Classifications

target_organs

Lagerklasse

wgk

flash_point_f

flash_point_c

Dokumentation

Analysenzertifikate (COA)

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