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Merck

43999

Supelco

5-Hydroxy-omeprazol

analytical standard

Synonym(e):

4-Methoxy-6-{[(5-methoxy-1H-benzimidazol-2-yl)-sulfinyl]-methyl}-5-methyl-3-pyridinmethanol, 5-Methoxy-2-{[(5-hydroxymethyl-4-methoxy-3-methyl-2-pyridinyl)-methyl]-sulfinyl}-1H-benzimidazol

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

Empirische Formel (Hill-System):
C17H19N3O4S
CAS-Nummer:
Molekulargewicht:
361.42
Beilstein:
8439890
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥95.0% (HPLC)

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-8°C

SMILES String

O=S(CC1=NC=C(CO)C(OC)=C1C)C2=NC3=CC(OC)=CC=C3N2

InChI

1S/C17H19N3O4S/c1-10-15(18-7-11(8-21)16(10)24-3)9-25(22)17-19-13-5-4-12(23-2)6-14(13)20-17/h4-7,21H,8-9H2,1-3H3,(H,19,20)

InChIKey

CMZHQFXXAAIBKE-UHFFFAOYSA-N

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Exclamation mark

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

J Olsson et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 875(1), 329-332 (2008-06-25)
The present paper demonstrates the enantiomeric separation of omeprazole and its metabolite 5-hydroxyomeprazole performed with open tubular capillary electrochromatography (OT-CEC). The protein avidin was used as the chiral selector. Avidin was immobilized by a Schiffs base type of reaction where
Valerie A Frerichs et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 824(1-2), 71-80 (2005-07-20)
A method has been developed and validated for the quantitation of midazolam, alphahydroxy-midazolam, omeprazole, and hydroxyomeprazole from one 250 microL sample of human plasma using high performance liquid chromatography coupled to tandem mass spectrometry. The method was validated for a
Ersin Gumus et al.
European journal of clinical pharmacology, 68(5), 629-636 (2011-11-15)
Lansoprazole, a cytochrome P450 2C19 (CYP2C19) substrate, has been widely used in children to manage acid-related diseases. CYP2C19 exhibits marked genetic polymorphisms, and distribution of these polymorphisms varies among different ethnic groups. There is limited data regarding the use of
Eileen B Lawson et al.
European journal of clinical pharmacology, 68(4), 407-413 (2011-10-20)
To develop a limited sampling strategy (LSS) to predict area under the concentration-time curve (AUC) ratios of omeprazole (AUC(OPZ)) to its metabolites 5-hydroxyomeprazole (AUC(5OH)) and omeprazole sulfone (AUC(SUL)) as phenotyping parameters for cytochrome P450 (CYP) 2C19 and 3A. Data were
S Rosenborg et al.
Clinical pharmacology and therapeutics, 88(3), 343-346 (2010-07-30)
Noscapine and glucosamine reportedly interact with warfarin. We investigated the effects of these drugs on various cytochrome P450 (CYP) activity markers. Twelve healthy subjects were phenotyped at baseline and during separate treatments with noscapine and glucosamine. Whereas glucosamine had no

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