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Merck

34004

Supelco

Ipronidazol-OH

VETRANAL®, analytical standard

Synonym(e):

2-(1-Methyl-5-nitro-1H-imidazol-2-yl)-propan-2-ol, Hydroxy-ipronidazol, IPZOH

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About This Item

Empirische Formel (Hill-System):
C7H11N3O3
CAS-Nummer:
Molekulargewicht:
185.18
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)

Format

neat

SMILES String

Cn1c(cnc1C(C)(C)O)[N+]([O-])=O

InChI

1S/C7H11N3O3/c1-7(2,11)6-8-4-5(9(6)3)10(12)13/h4,11H,1-3H3

InChIKey

DTHPMNDYKOSVFR-UHFFFAOYSA-N

Allgemeine Beschreibung

Ipronidazole-OH is a metabolite of nitroimidazole antibiotics, used in veterinary medicine to combat anaerobic bacterial and parasitic infections.

Anwendung

Ipronidazole-OH may be used as a reference standard in the determination of nitroimidazole drug and its corresponding hydroxy metabolites in aquaculture tissue by ultra-high performance liquid chromatography coupled to tandem mass spectrometry.
Ipronidazole-OH may be used as an analytical reference standard for the determination of the analyte in:
  • Cosmetics using high-performance liquid chromatography coupled to electrospray ionization-tandem mass spectrometry (HPLC-ESI-MS/MS).
  • Aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Determination of nitroimidazole residues in aquaculture tissue using ultra high performance liquid chromatography coupled to tandem mass spectrometry.
Gadaj A, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 960(6), 105-115 (2014)
Simultaneous determination of 15 nitroimidazoles in cosmetics by HPLC coupled with electrospray ionization-tandem mass spectrometry.
Meng S-X, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 97(6), 1538-1545 (2014)
Kamila Mitrowska et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 34(4), 573-581 (2016-11-15)
Nitroimidazoles are not authorised for the treatment of honey bees in the European Union. However, they can be found in honey largely because they are illegally used in apiculture for the treatment of Nosema. The aim of the study was
Anton Kaufmann et al.
Journal of the American Society for Mass Spectrometry, 28(12), 2705-2715 (2017-09-14)
Targeted residue screening requires the use of reference substances in order to identify potential residues. This becomes a difficult issue when using multi-residue methods capable of analyzing several hundreds of analytes. Therefore, the capability of in silico fragmentation based on
Simone Moretti et al.
Analytica chimica acta, 1032, 56-67 (2018-08-26)
A multiclass screening method to detect fifty-three forbidden substances by liquid-chromatography coupled to hybrid high-resolution mass spectrometry (LC-Q-Orbitrap) was developed and validated in bovine bile and urine. Eight classes of compounds were included in the method's scope (β-agonists, corticosteroids, nitroimidazoles

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