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Merck

33998

Supelco

Melengestrolacetat

VETRANAL®, analytical standard

Synonym(e):

17α-Acetoxy-6-methyl-16-methylen-4,6-pregnadien-3,20-dion, MGA

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About This Item

Empirische Formel (Hill-System):
C25H32O4
CAS-Nummer:
Molekulargewicht:
396.52
Beilstein:
2066919
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Produktlinie

VETRANAL®

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

202-204 °C (lit.)

Anwendung(en)

clinical testing

Format

neat

SMILES String

[H][C@]12CC[C@@]3(C)[C@@]([H])(CC(=C)[C@]3(OC(C)=O)C(C)=O)[C@]1([H])C=C(C)C4=CC(=O)CC[C@]24C

InChI

1S/C25H32O4/c1-14-11-19-20(23(5)9-7-18(28)13-21(14)23)8-10-24(6)22(19)12-15(2)25(24,16(3)26)29-17(4)27/h11,13,19-20,22H,2,7-10,12H2,1,3-6H3/t19-,20+,22+,23-,24+,25+/m1/s1

InChIKey

UDKABVSQKJNZBH-DWNQPYOZSA-N

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Allgemeine Beschreibung

Melengestrol acetate belongs to the family of hormones. This acetylgestagen compound is known to elicit a gestagenic effect in vivo.

Anwendung

Melengestrol acetate may be used as a reference standard for the determination of the analyte in:
  • Milk using turborFlow online solid phase extraction (SPE) combined with liquid chromatography-tandem mass spectrometry (LC-MS/MS).
  • Kidney fats by ultra-performance convergence chromatography-tandem mass spectrometry.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Health hazard

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Repr. 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves


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Kunden haben sich ebenfalls angesehen

Simultaneous determination of seven gestagens in kidney fats by Ultra Performance Convergence Chromatography tandem mass spectrometry.
Tao Y, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 988, 143-148 (2015)
Madis Lõhmus et al.
Analytica chimica acta, 586(1-2), 233-238 (2007-03-28)
The use of gestagens in animal fattening is prohibited within the European Union. Recently, the use of spectrometric methods for the detection and confirmation of banned substances was made obligatory. Therefore, conventional high-performance liquid chromatographic (HPLC) methods have been superseded.
D R Eborn et al.
Journal of animal science, 91(2), 666-672 (2012-12-12)
Two experiments were conducted over 3 yr to determine pregnancy rates in beef heifers after a timed AI in response to the 7-11 Synch protocol. In Exp. 1, 179 heifers were either fed melengestrol acetate (MGA; 7-11 Synch) or given
D McAloose et al.
Veterinary pathology, 44(3), 320-326 (2007-05-11)
Melengestrol acetate (MGA), a potent synthetic progestin, has been used as a contraceptive in zoo felids since 1975. Mammary gland carcinomas have been linked to MGA treatment in zoo felids, but the histologic features of these tumors and steroid receptor
G A Perry et al.
Theriogenology, 71(5), 775-779 (2008-11-14)
Treatment with GnRH at the onset of standing estrus increased pregnancy percentages and circulating concentrations of progesterone in repeat breeder dairy cows. The objective of this study was to determine the effect of treatment with GnRH at AI on concentrations

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