MABF156B

Anti-CD44 (human/mouse), redFluor^® 710, clone IM7. Antibody

clone IM7, from rat, redFluor^® 710

• Synonym(e): CD44 antigen, Extracellular matrix receptor III (ECMR-III), GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Hermes antigen, Hyaluronate receptor, Lymphocyte antigen 24 (Ly-24), Phagocytic glycoprotein 1 (PGP-1), Phagocytic glycoprotein I (PGP-I), CD44
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.45

Eigenschaften

• Biologische Quelle: rat
• Qualitätsniveau: 100
• Konjugat: redFluor^® 710
• Antikörperform: purified antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: IM7, monoclonal
• Speziesreaktivität: mouse, human
• Verpackung: antibody small pack of 25 μg
• Methode(n): flow cytometry: suitable
• UniProt-Hinterlegungsnummer: P15379
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CD44(960) ; mouse ... Cd44(12505)

Beschreibung

Allgemeine Beschreibung

The IM7 antibody recognizes CD44, a ubiquitously expressed cell surface receptor which is important for extracellular matrix organization, cell-cell and cell-matrix adhesion and migration. CD44 may be expressed in a number of different isoforms (splice variants) from the most typical or “standard” form, known as CD44s, to variants designated CD44v, e.g. CD44v1 or CD44v6. These receptors interact with several ligands, but most often associate with an extracellular matrix component hyaluronate, through which it mediates adhesion.The IM7 antibody may be used for detection of all isoforms of CD44, as it recognizes constant epitopes near the extracellular proximal domain. (Xu et al, 2002, J. Leukoc. Biol. 72:1133-1141).

Immunogen

Immunogen information for this antibody is proprietary information.

Anwendung

Research Category
Entzündung & Immunologie

Research Sub Category
Immunoglobuline & Immunologie

Anti-CD44 (human/mouse), redFluor^® 710, clone IM7 Antibody is an antibody against CD44 for use in Flow Cytometry.

Qualität

This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.5 μg from a representative lot detected CD44 in one million C57Bl/6 splenocytes.

Physikalische Form

Purified by size-exclusion chromatography

Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Sonstige Hinweise

Concentration: Please refer to lot specific datasheet.

Rechtliche Hinweise

redFluor is a registered trademark of Tonbo Biotechnologies

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable