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Merck

MAB1155

Sigma-Aldrich

Anti-Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2

clone MMHAR-2, Chemicon®, from mouse

Synonym(e):

CD118

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

MMHAR-2, monoclonal

Speziesreaktivität

human

Hersteller/Markenname

Chemicon®

Methode(n)

flow cytometry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable

Isotyp

IgG2a

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... IFNA1(3439)

Spezifität

Reacts with Human Interferon alpha/beta Receptor Chain 2 (CD118). Antibody neutralizes human interferon alpha receptor, interacts with extracellular domain, binds to human interferon alpha receptor with high affinity, and blocks biological action of Type I interferons.

Immunogen

Human Interferon alpha/beta Receptor Chain 2

Anwendung

Research Category
Entzündung & Immunologie
Research Sub Category
Cytokine & Cytokin-Rezeptoren
Anti-Interferon-α/β Receptor Chain 2 Antibody, clone MMHAR-2 is an antibody against Interferon-α/β Receptor Chain 2 for use in FC, IP, IH.
Biological Studies

Immunoprecipitation: (1-5 μg/mL)

Immunohistochemistry: (1μg/mL)

Flow cytometry: (1 μg/10 mL - block cells with 50% human AB serum)

Optimal working dilutions must be determined by end user.

Physikalische Form

Format: Purified
Purified immunoglobulin. Liquid in PBS containing 0.1% bovine serum albumin (BSA).

Lagerung und Haltbarkeit

Maintain frozen at -20°C or below for retention of full activity, for up to 12 months. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Chlamydia trachomatis-infected epithelial cells and fibroblasts retain the ability to express surface-presented major histocompatibility complex class I molecules.
Kagebein, D; Gutjahr, M; Gro?e, C; Vogel, AB; Rodel, J; Knittler, MR
Infection and Immunity null
G Pollara et al.
Scandinavian journal of immunology, 63(3), 151-154 (2006-02-28)
The central role of dendritic cells (DC) in the initiation of immune responses requires these cells to be able to determine the degree of danger in their microenvironment. Abrogating the activity of type I interferon (IFN) secreted after lipopolysaccharide (LPS)
Ting Zhang et al.
Hepatology (Baltimore, Md.), 42(4), 819-827 (2005-09-22)
The chronicity of hepatitis C virus (HCV) infection raises the question of how HCV is able to persist in hepatic cells. We show that human primary hepatocytes and human hepatic cell lines (Huh7 and HepG2) spontaneously produce interferon (IFN)-alpha that
Aura Muntasell et al.
Frontiers in immunology, 4, 40-40 (2013-02-27)
Natural killer (NK) cells play an important role in the defense against viral infections. Activation of resting NK cells is tightly controlled by the balance of surface inhibitory and activating receptors and aided by cytokines released by accessory cells along
Joshua Ogony et al.
Breast cancer research : BCR, 18(1), 25-25 (2016-02-22)
Inflammatory breast cancer (IBC) is a very aggressive and lethal subtype of breast cancer that accounts for about 4 % of all breast cancers diagnosed in the United States. Despite the efforts of several investigators to identify the molecular factors driving

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