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DR1041

Sigma-Aldrich

Anti-TIP60 Rabbit pAb

liquid, Calbiochem®

Synonym(e):

Anti-HIV-1 Tat interactive protein, Anti-cPLA2-interaction protein

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.43

Biologische Quelle

rabbit

Qualitätsniveau

100

Antikörperform

serum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

liquid

Enthält

≤0.1% sodium azide as preservative

Speziesreaktivität

human

Hersteller/Markenname

Calbiochem®

Lagerbedingungen

OK to freeze
avoid repeated freeze/thaw cycles

Isotyp

IgG

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... KAT5(10524)

Allgemeine Beschreibung

Rabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~60 kDa TIP60 protein.
Recognizes the ~60 kDa TIP60 protein in Saos-2 cells.
This Anti-TIP60 Rabbit pAb is validated for use in Immunoblotting, Immunoprecipitation for the detection of TIP60.

Immunogen

recombinant, human TIP60 protein

Anwendung


Immunoblotting (1:3000)
Immunoprecipitation (1:100)

Warnhinweis

Toxicity: Standard Handling (A)

Hinweis zur Analyse

Positive Control
Saos-2 cells

Sonstige Hinweise

Murr, R., et al. 2006. Nat. Cell Biol.8, 91.
Sykes, S.M., et al. 2006. Mol. Cell24, 841.
Tang, Y., et al. 2006. Mol. Cell24, 827.
Frank, S.R., et al. 2003. EMBO Rep.6, 575.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Analysenzertifikate (COA)

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Parkinson's disease (PD) is a chronic and progressive neurodegenerative disorder. While most PD cases are idiopathic, the known genetic causes of PD are useful to understand common disease mechanisms. Recent data suggests that autophagy is regulated by protein acetylation mediated
Ling-Jun Zhao et al.
Virology, 499, 178-184 (2016-09-25)
The adenovirus E1A 243R oncoprotein targets TRRAP, a scaffold protein that assembles histone acetyltransferase (HAT) complexes, such as the NuA4/Tip60 complex which mediates transcriptional activity of the proto-oncogene MYC and helps determine the cancer cell phenotype. How E1A transforms cells
Cheng Wang et al.
Communications biology, 3(1), 268-268 (2020-05-29)
Cisplatin and other platinum-based compounds are frequently used to treat breast cancer, but their utility is severely compromised by drug resistance. Many genes dictating drug responsiveness are subject to pre-mRNA alternative splicing which is regulated by key kinases such as
Kristin A Krukenberg et al.
Cell reports, 8(6), 1808-1818 (2014-09-10)
Poly(ADP-ribose) polymerases (PARPs) catalyze poly(ADP-ribose) addition onto proteins, an important posttranslational modification involved in transcription, DNA damage repair, and stem cell identity. Previous studies established the activation of PARP1 in response to DNA damage, but little is known about PARP1
Yixin Dong et al.
Molecular and cellular biology, 37(19) (2017-07-12)
Global histone hyperacetylation is suggested to play a critical role for replacement of histones by transition proteins and protamines to compact the genome during spermiogenesis. However, the underlying mechanisms for hyperacetylation-mediated histone replacement remains poorly understood. Here, we report that
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