8.08259

2,2,2-Trifluoroethanol

for synthesis

• Synonym(e): 2,2,2-Trifluoroethanol
• Empirische Formel (Hill-System): C₂H₃F₃O
• CAS-Nummer: 75-89-8
• Molekulargewicht: 100.04
• MDL-Nummer: MFCD00004672
• UNSPSC-Code: 12352104
• EG-Index-Nummer: 200-913-6
• NACRES: NA.22
• bp: 73.6 °C/1013 hPa

Eigenschaften

• Qualität: for synthesis
• Qualitätsniveau: 200
• Dampfdruck: 70.9 hPa ( 20 °C)
• Assay: ≥99% (GC)
• Form: liquid
• Wirksamkeit: 240 mg/kg LD₅₀, oral (Rat); 1680 mg/kg LD₅₀, skin (Rat)
• Expl.-Gr.: 8.4-28.8 % (v/v)
• dilution: (for synthesis)
• pH-Wert: 7
• bp: 73.6 °C/1013 hPa
• mp (Schmelzpunkt): -43.5 °C
• Übergangstemp.: flash point 30 °C
• Dichte: 1.38 g/cm³ at 25 °C
• Lagertemp.: 2-30°C
• SMILES String: FC(F)(F)CO
• InChI: 1S/C2H3F3O/c3-2(4,5)1-6/h6H,1H2
• InChIKey: RHQDFWAXVIIEBN-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2,2,2-Trifluoroethanol (TFE) is a fluorinated compound used as a solvent in organic synthesis. Peptides and proteins are experimentally studied using TEE as a cosolvent. In TFE, hydrogen peroxide is effective for oxidizing sulfur compounds.

Anwendung

2,2,2-Trifluoroethanol is used as a solvent:

• In the preparation of nylon/Ag composite nanofibers by electrospinning method.
• To study the combination of two polymers PANI (polyaniline) and PHB (polyhydroxy-butyrate).

Leistungsmerkmale und Vorteile

2,2,2-Trifluoroethanol is more acidic than ethanol due to the presence of electronegative trifluoromethyl group.

Sicherheitshinweise

• Piktogramme: GHS02,GHS05,GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H226 - H301 + H331 - H318 - H360F - H373
• P-Sätze: P202 - P210 - P280 - P301 + P310 - P304 + P340 + P311 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Dam. 1 - Flam. Liq. 3 - Repr. 1B - STOT RE 2 Inhalation
• Zielorgane: Blood
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 1
• Flammpunkt (°F): 86.0 °F - closed cup
• Flammpunkt (°C): 30 °C - closed cup