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Eshmuno^® CMX Resin

Eshmuno® CMX

• Synonym(e): Eshmuno^® CMX
• UNSPSC-Code: 47101511

Eigenschaften

• ligand: (Carboxy and Alkyl Group)
• Qualitätsniveau: 400
• Sterilität: sterile (Caustic Stable)
• Form: resin
• spezifische(r) Analyt(en): MAbs
• Parameter: 300 cm/hr flow rate; 8 bar max. pressure
• Aktive Matrixgruppe: polymer, polyvinyl ether
• Mittlere Partikelgröße: 50 μm
• Kapazität: 60 mg binding capacity (pIgG/ml of resin)
• Anwendung(en): ADC; mAb
• Trenntechnik: mixed mode
• Lagertemp.: 2-30°C

Beschreibung

Allgemeine Beschreibung

Eshmuno^® CMX chromatography resin is a mixed mode chromatography resin built on the proven Eshmuno^® resin technology. This innovative resin combines weak cation exchange properties with hydrophobic interaction, providing high selectivity for Monoclonal Antibody (mAb), fusion protein and Antibody Drug Conjugate (ADCs) purification as well as separation of low molecular weight impurities, Host Cell Proteins (HCPs) and glycovariants.

Anwendung

Purification of mAbs, ADCs, fusion proteins

Leistungsmerkmale und Vorteile

Eshmuno^® CMX chromatography resin enables users to

• Intensify processes and decrease costs by reducing the number of chromatographic steps and buffer consumption
• Improve performance with higher recovery rates, high selectivity and superior dynamic binding capacity
• Improve the user experience with a broad operational window, simplified process development and easy column packing due to a rigid base bead

Rechtliche Hinweise

Eshmuno is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02
• Signalwort: Warning
• H-Sätze: H226
• P-Sätze: P210 - P233 - P240 - P241 - P242 - P243
• Gefahreneinstufungen: Flam. Liq. 3
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 95.0 °F
• Flammpunkt (°C): 35 °C