M-132

N-Methyl-N-trimethylsilyltrifluoracetamid

ampule of 10 × 1.2 mL, analytical standard, Cerilliant^®

• Synonym(e): N-Trimethylsilyl-N-methyltrifluoracetamid, MSTFA
• Lineare Formel: CF₃CON(CH₃)Si(CH₃)₃
• CAS-Nummer: 24589-78-4
• Molekulargewicht: 199.25
• Beilstein: 1941550
• EG-Nummer: 246-331-6
• MDL-Nummer: MFCD00000411
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329817869
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Dampfdichte: >1 (vs air)
• Dampfdruck: 8.8 mmHg ( 27 °C)
• Eignung der Reaktion: reagent type: derivatization reagent; reaction type: Acylations
• Verpackung: ampule of 10 × 1.2 mL
• Hersteller/Markenname: Cerilliant^®
• Methode(n): gas chromatography (GC): suitable
• Brechungsindex: n20/D 1.38 (lit.)
• bp: 130-132 °C (lit.)
• Dichte: 1.075 g/mL at 25 °C (lit.)
• Anwendung(en): forensics and toxicology
• Format: neat
• Lagertemp.: −20°C
• SMILES String: CN(C(=O)C(F)(F)F)[Si](C)(C)C
• InChI: 1S/C6H12F3NOSi/c1-10(12(2,3)4)5(11)6(7,8)9/h1-4H3
• InChIKey: MSPCIZMDDUQPGJ-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

MSTFA (N-Methyl-N-trimethylsilylfluoroacetamide) is an important trimethylsilyl reagent, and a commonly applied reagent since it is highly reactive towards a broad range of compound classes. GC-MS optimization studies reveal the use of this reagent either alone or in combination with 1% of trimethylchlorosilane as a catalyst for silylation of complex mixtures. It has similar reactivity as BSA and BSTFA.

Anwendung

MSTFA reagent may be used as a derivatizing agent in the following:

• Analysis of estrogen steroids such as estrone (E1), 17α-ethinylestradiol (EE2), and trenbolone acetate metabolites, melengestrol in environmental matrices using gas chromatography coupled to mass spectrometry (GC-MS).
• Quantification of ibuprofen, naproxen, ketoprofen, and diclofenac in wastewater samples using gas chromatography coupled to mass spectrometry (GC-MS).

Leistungsmerkmale und Vorteile

• Very volatile of TMS-acetamides.
• More volatile than BSA or BSTFA but with similar silylation strength.
• Useful in the analysis of volatile trace materials.
• Used in the preparation of volatile and thermally stable derivatives for GC and MS analysis.

Rechtliche Hinweise

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Warning
• H-Sätze: H226,H315,H319,H335
• P-Sätze: P210 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 3 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 78.8 °F - closed cup
• Flammpunkt (°C): 26 °C - closed cup