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860510P

Avanti

C10 Ceramide (d18:1/10:0)

Avanti Research™ - A Croda Brand 860510P, powder

Synonym(e):

N-decanoyl-D-erythro-sphingosine

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About This Item

Empirische Formel (Hill-System):
C28H55NO3
CAS-Nummer:
111122-57-7
Molekulargewicht:
453.74
MDL-Nummer:
MFCD02259134
UNSPSC-Code:
12352211
NACRES:
NA.25

Form

powder

Verpackung

pkg of 1 × 5 mg (860510P-5mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 860510P

Lipid-Typ

sphingolipids

Versandbedingung

dry ice

Lagertemp.

−20°C

SMILES String

OC[C@]([H])(NC(CCCCCCCCC)=O)[C@]([H])(O)/C=C/CCCCCCCCCCCCC

InChI

1S/C28H55NO3/c1-3-5-7-9-11-12-13-14-15-16-18-19-21-23-27(31)26(25-30)29-28(32)24-22-20-17-10-8-6-4-2/h21,23,26-27,30-31H,3-20,22,24-25H2,1-2H3,(H,29,32)/b23-21+/t26-,27+/m0/s1

InChIKey

FDWVAQFAMZLCAX-NBNLIBPQSA-N

Verwandte Kategorien

Allgemeine Beschreibung

C10 Ceramide (d18:1/10:0) is a synthetic ceramide containing sphingosine with decanoic acid. It has a short acyl chain length than sphingosine acyl chain.

Anwendung

C10 Ceramide (d18:1/10:0) or N-decanoyl-D-erythro-sphingosine has been used:
  • as an internal standard in galactocerebrosidase (GALC) assay
  • to study its role on the physical properties of edible organogels and on their ability to induce cell death of various cancer cell lines
  • to study its mixing behavior with other ceramides having the same sphingosine base but varying N-linked acyl chain length

Biochem./physiol. Wirkung

Ceramides modulate stress responses and inflammation. It also controls cell differentiation, proliferation and apoptosis.

Verpackung

5 mL Amber Glass Screw Cap Vial (860510P-5mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Joseph J Orsini et al.
Clinical biochemistry, 42(9), 877-884 (2009-03-26)
The aim of this study was to develop a newborn screening algorithm for Krabbe disease. We measured the galactocerebrosidase activity of 139,074 anonymous newborns, 56 known carriers, and 16 Krabbe patients using a tandem mass spectrometry method. The activities were
Fernando Dupuy et al.
Chemistry and physics of lipids, 165(6), 615-629 (2012-07-12)
The organization of lipids within membranes strongly depends on the interaction with other lipid and protein molecules. Sphingolipids comprise a structurally diverse family, the ceramides being some of the simplest members. Although small chemical modifications of ceramide structure, such as
Meenu N Perera et al.
Chemistry and physics of lipids, 194, 110-116 (2015-09-27)
A ceramide commonly found in mammalian cells, C16-ceramide (N-palmitoyl-d-erythro-sphingosine), is capable of forming large, protein-permeable channels in the mitochondrial outer membrane (MOM). However, C16-ceramide is unable to permeabilize the plasma membrane of erythrocytes. This specificity is unexpected considering that ceramide
Michael A Rogers et al.
Food science & nutrition, 5(3), 579-587 (2017-06-03)
Short-chain ceramides, such as N-acetoyl-d-erythro-sphingosine (C2), have a remarkable ability to structure edible oils, such as canola oil, into self-standing organogels without any added saturated or trans fats. These short-chain ceramides are ubiquitously found in foods ranging from eggs to
Zhixing Wang et al.
The Journal of investigative dermatology, 133(3), 668-676 (2012-10-26)
The stratum corneum is composed of protein-enriched corneocytes embedded in an intercellular matrix of nonpolar lipids organized as lamellar layers and giving rise to epidermal permeability barrier (EPB). EPB defects have an important role in the pathophysiology of skin diseases
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