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810176P

Avanti

18:1-12:0 NBD PA

Avanti Research™ - A Croda Brand 810176P, powder

Synonym(e):

1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt)

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About This Item

Empirische Formel (Hill-System):
C39H68N5O11P
CAS-Nummer:
384833-04-9
Molekulargewicht:
813.96
MDL-Nummer:
MFCD22495291
UNSPSC-Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

Form

powder

Verpackung

pkg of 1 × 1 mg (810176P-1mg)

Hersteller/Markenname

Avanti Research™ - A Croda Brand 810176P

Versandbedingung

dry ice

Lagertemp.

−20°C

Verwandte Kategorien

Allgemeine Beschreibung

Phosphatidic acid (PA) is an anionic cellular glycerophospholipid constituting 1-4% of membrane lipids. It possesses a phosphomonoester polar head group and two long hydrophobic acyl chains. NBD PA is a fluorescently labelled lipid with the fluorophore, 7-nitrobenz-2-oxa-1,3-diazol-4-yl (NBD) at the sn-2 fatty acid of PA.

Anwendung

18:1-12:0 NBD PA or 1-oleoyl-2-{12-[(7-nitro-2-1,3-benzoxadiazol-4-yl)amino]dodecanoyl}-sn-glycero-3-phosphate (ammonium salt) is suitable: for the in vitro enzyme activity assay of galactolipase, for NBD-PA and NBD phosphatidyl choline uptake assays, to measure lipid transfer specificity of Ups1 mutants

Biochem./physiol. Wirkung

Phosphatidic acid (PA) is implicated in many membrane fusion and membrane fission events, such as fission of Golgi membranes. It is a bioactive lipid and a secondary messenger.

Verpackung

5 mL Amber Glass Screw Cap Vial (810176P-1mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

No data available

Flammpunkt (°C)

No data available

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Analysenzertifikate (COA)

Lot/Batch Number

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Die Dokumentenbibliothek aufrufen

Lipid second messengers and Receptors
Encyclopedia of Endocrine Diseases, 77(3), 329-334 (2004)
Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins
Miliara X, et al.
Nature Communications, 10(1), 1130-1130 (2019)
Anh H Ngo et al.
The New phytologist, 219(1), 163-175 (2018-04-15)
Phospholipases play crucial roles in plant membrane lipid homeostasis. Nonspecific phospholipase C (NPCs) establish a unique class of phospholipases found only in plants and certain bacteria. Here, we show that two previously uncharacterized NPC isoforms, NPC2 and NPC6, are required
Xeni Miliara et al.
Nature communications, 10(1), 1130-1130 (2019-03-10)
Conserved lipid transfer proteins of the Ups/PRELI family regulate lipid accumulation in mitochondria by shuttling phospholipids in a lipid-specific manner across the intermembrane space. Here, we combine structural analysis, unbiased genetic approaches in yeast and molecular dynamics simulations to unravel
Mikhail A Zhukovsky et al.
FEBS letters, 593(17), 2428-2451 (2019-08-01)
Phosphatidic acid (PA) is the simplest cellular glycerophospholipid characterized by unique biophysical properties: a small headgroup; negative charge; and a phosphomonoester group. Upon interaction with lysine or arginine, PA charge increases from -1 to -2 and this change stabilizes protein-lipid
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