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Merck

750332C

Avanti

14:0 Cardiolipin (sodium salt)

1′,3′-bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (sodium salt), chloroform

Synonym(e):

1,1′,2,2′-tetratetradecanoyl cardiolipin (sodium salt); CL(1′-[14:0/14:0],3′-[14:0/14:0])

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About This Item

Empirische Formel (Hill-System):
C65H124Na2O17P2
CAS-Nummer:
Molekulargewicht:
1285.60
UNSPSC-Code:
51191904
NACRES:
NA.25

Assay

>99% (TLC)

Form

solution

Verpackung

pkg of 1 × 2.5 mL (750332C-25mg)
pkg of 2 × 4 mL (750332C-200mg)

Hersteller/Markenname

Avanti Research - A Croda Brand 750332C

Konzentration

10 mg/mL (750332C-25mg)
25 mg/mL (750332C-200mg)

Lipid-Typ

phospholipids
cardiolipins

Versandbedingung

dry ice

Lagertemp.

−20°C

Allgemeine Beschreibung

Cardiolipin, the mitochondrial-specific phospholipid, helps maintain mitochondrial function, membrane potential and structural support for the inner mitochondrial membrane and the proteins in it. Concentration and composition changes of cardiolipin have been implicated in pathological conditions including ischemia, hypothyroidism, aging, heart failure and cardioskeletal myopathy (Barth syndrome). Cardiolipin has also been shown as a signaling molecule in apoptosis.

Anwendung

14:0 Cardiolipin (sodium salt) has been used for the mass spectrometry (MS) analysis to determine the structure of lipid A.

Verpackung

5 mL Clear Glass Sealed Ampule (750332C-200mg)
5 mL Clear Glass Sealed Ampule (750332C-25mg)

Rechtliche Hinweise

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Piktogramme

Skull and crossbonesHealth hazard

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Zielorgane

Central nervous system, Liver,Kidney

WGK

WGK 3


Analysenzertifikate (COA)

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Rapid lipid a structure determination via surface acoustic wave nebulization and hierarchical tandem mass spectrometry algorithm
Yoon SH, et al.
Rapid Communications in Mass Spectrometry, 30(23), 2555-2560 (2016)
Role of cardiolipin alterations in mitochondrial dysfunction and disease
Chicco AJ and Sparagna GC
American Journal of Physiology. Cell Physiology, 292(1), C33-C44 (2007)
Vladimir B Ritov et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 831(1-2), 63-71 (2005-12-13)
Cardiolipin is a phospholipid that is specific to the inner mitochondrial membrane and essential for numerous mitochondrial functions. Accordingly, a quantitative assay for cardiolipin can be a valuable aspect of assessing mitochondrial content and functional capacity. The current study was
Na Li et al.
Analytical chemistry, 91(24), 15873-15882 (2019-11-14)
The matrix plays a prominent role in expanding the ability of matrix assisted laser desorption/ionization mass spectrometry (MALDI MS). However, on account of the unclarity of necessary properties of the matrix in MALDI MS, development of a new matrix is
Yuchen Sun et al.
Metabolites, 9(11) (2019-11-07)
Extracellular vesicles (EVs) consist of lipid bilayers, occur in various biofluids, and are invaluable in biomarker screening. Liquid chromatography coupled with high-resolution mass spectrometry (LC-MS) was recently used to study comprehensive EV lipid profiles in vitro. The aim of this

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