F3401

2-Fluor-anilin

≥99%

• Synonym(e): 1-Amino-2-fluor-benzol
• Lineare Formel: FC₆H₄NH₂
• CAS-Nummer: 348-54-9
• Molekulargewicht: 111.12
• Beilstein: 1524219
• EG-Nummer: 206-478-9
• MDL-Nummer: MFCD00007642
• UNSPSC-Code: 12352116
• PubChem Substanz-ID: 24894844
• NACRES: NA.25

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥99%
• Brechungsindex: n20/D 1.544 (lit.)
• bp: 182-183 °C (lit.)
• mp (Schmelzpunkt): −29 °C (lit.)
• Dichte: 1.151 g/mL at 25 °C (lit.)
• SMILES String: Nc1ccccc1F
• InChI: 1S/C6H6FN/c7-5-3-1-2-4-6(5)8/h1-4H,8H2
• InChIKey: FTZQXOJYPFINKJ-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

The metabolism and excretion of the xenobiotic compound 2-fluoroaniline is important due to human exposure in manufacturing. It is found to be very efficiently metabolized, primarily by 4-hydroxylation with subsequent sulfate or glucuronide formation. N-Acetylation is also observed. At least 80% of the dose is excreted in the urine within 24 hr. 2-Fluoroaniline exerts its nephrotoxic effect through 4-hyroxylation and subsequent p-benzoquinonimine formation.

Sicherheitshinweise

• Piktogramme: GHS02,GHS08,GHS05,GHS07,GHS09
• Signalwort: Danger
• H-Sätze: H226,H302,H314,H373,H410
• P-Sätze: P210 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P314
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1C - STOT RE 2
• Zielorgane: Blood,hematopoietic system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 2
• Flammpunkt (°F): 140.0 °F - closed cup
• Flammpunkt (°C): 60 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter