900399

SLAP N-Bn Pip Reagent

95%

• Synonym(e): N¹-Benzyl-N¹-((trimethylsilyl)methyl)ethane-1,2-diamine
• Empirische Formel (Hill-System): C₁₃H₂₄N₂Si
• CAS-Nummer: 1908469-38-4
• Molekulargewicht: 236.43
• MDL-Nummer: MFCD30183339
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329769827
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 95%
• Form: liquid (paste)
• Brechungsindex: n/D 1.5071
• Dichte: 0.9366 g/mL
• Funktionelle Gruppe: amine; phenyl
• Lagertemp.: −20°C
• SMILES String: [Si](CN(CCN)Cc1ccccc1)(C)(C)C
• InChI: 1S/C13H24N2Si/c1-16(2,3)12-15(10-9-14)11-13-7-5-4-6-8-13/h4-8H,9-12,14H2,1-3H3
• InChIKey: OIVATBFWYNCAKW-UHFFFAOYSA-N

Beschreibung

Anwendung

Silicon amine protocol (SLAP) reagents, in conjunction with aldehydes and ketones, form N-unprotected piperazines via photocatalytic cross-coupling with Ir[(ppy)₂dtbbpy]PF₆ (747769). Heteroaromatic, aromatic, and aliphatic aldehydes are well tolerated, as are structurally and stereochemically complex SLAP reagents. This product was introduced in collaboration with the Bode Research Group and provides a tin-free alternative to SnAP (tin amine protocol) reagents for piperazine synthesis.

Sonstige Hinweise

• Technology Spotlight: SLAP Reagents for Piperazine Synthesis
• Silicon Amine Reagents for the Photocatalytic Synthesis of Piperazines from Aldehydes and Ketones
• Lewis Acid Induced Toggle from Ir(II) to Ir(IV) Pathways in Photocatalytic Reactions: Synthesis of Thiomorpholines and Thiazepanes from Aldehydes and SLAP Reagents.
• Continuous Flow Synthesis of Morpholines and Oxazepanes with Silicon Amine Protocol (SLAP) Reagents and Lewis Acid Facilitated Photoredox Catalysis

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): 198.0 °F
• Flammpunkt (°C): 92.2 °C