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Trimethylamine-d9 N-Oxide
98 atom % D, 98% (CP)
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About This Item
Empfohlene Produkte
Isotopenreinheit
98 atom % D
Assay
98% (CP)
Form
solid
Methode(n)
bio NMR: suitable
Massenverschiebung
M+9
SMILES String
[O-][N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H]
InChI
1S/C3H9NO/c1-4(2,3)5/h1-3H3/i1D3,2D3,3D3
InChIKey
UYPYRKYUKCHHIB-GQALSZNTSA-N
Verwandte Kategorien
Allgemeine Beschreibung
Trimethylamine-d9 is isotopically enriched molecule.
Anwendung
Trimethylamine-d9 N-oxide is used in the stability of hydrogen bonding between peptide, water with trimethylamine N-oxide.It is also used as an internal standard for the quantification of trimethylamine N-oxide by GC- or LC-MS.
Verpackung
This product may be available from bulk stock and can be packaged on demand. For information on pricing, availability and packaging, please contact Stable Isotopes Customer Service.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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Biophysical journal, 97(9), 2559-2566 (2009-11-04)
Trimethylamine N-oxide (TMAO) is a naturally occurring osmolyte that stabilizes proteins, induces folding, and counteracts the denaturing effects of urea, pressure, and ice. To establish the mechanism behind these effects, isotopic substitution neutron-scattering measurements were performed on aqueous solutions of
The Journal of toxicological sciences, 43(6), 387-393 (2018-06-08)
Medicinal carnitine-derived and dietary-derived malodorous trimethylamine and its non-malodorous metabolite trimethylamine N-oxide were historically regarded as nontoxic. Clinical and toxicological interest has recently arisen because of their potential association with atherosclerosis. We previously reported a human physiologically based pharmacokinetic (PBPK)
Nutrition (Burbank, Los Angeles County, Calif.), 66, 29-37 (2019-06-16)
A plant-based diet has been associated with a reduced risk of cardiovascular (CV) diseases. This study aimed to determine the levels and correlations of CV-related biomarkers and the beneficial role of dietary habits. A total of 63 healthy vegetarians (n = 32)
Analytical biochemistry, 455, 35-40 (2014-04-08)
Trimethylamine-N-oxide (TMAO) levels in blood predict future risk for major adverse cardiac events including myocardial infarction, stroke, and death. Thus, the rapid determination of circulating TMAO concentration is of clinical interest. Here we report a method to measure TMAO in
ESC heart failure, 7(1), 188-193 (2020-01-22)
Accumulating evidence has demonstrated that intestinal microbiota-dependent trimethylamine N-oxide (TMAO) is involved in the pathogenesis of various cardiovascular diseases. The present study was designed to investigate the prognostic value of TMAO in patients with chronic heart failure (CHF) after myocardial
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