592277

2-Chlorbenzimidazol

98%

• Empirische Formel (Hill-System): C₇H₅ClN₂
• CAS-Nummer: 4857-06-1
• Molekulargewicht: 152.58
• EG-Nummer: 225-453-3
• MDL-Nummer: MFCD00051944
• UNSPSC-Code: 12352100
• eCl@ss: 32151902
• PubChem Substanz-ID: 24881379
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: 98%
• Form: solid
• mp (Schmelzpunkt): 207-211 °C (lit.)
• Funktionelle Gruppe: chloro
• SMILES String: Clc1nc2ccccc2[nH]1
• InChI: 1S/C7H5ClN2/c8-7-9-5-3-1-2-4-6(5)10-7/h1-4H,(H,9,10)
• InChIKey: AYPSHJCKSDNETA-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

2-Chlorobenzimidazole can be synthesized by reacting benzimidazole-2-one with phosphoryl chloride in the presence of phenol.

Anwendung

2-Chlorobenzimidazole can be used to synthesize the following:

• 1-methyl-2-chlorobenzimidazole via reaction with dimethyl sulfate
• 1-ethyl-2-chlorobenzimidazole via reaction with diethyl sulfate
• 1-benzyl-2-chlorobenzimidazole via reaction with benzyl chloride
• 2-chloro-4,5,6,7-tetrabromobenzimidazole via bromination with bromine

It may be used as a building block to synthesize 4-amino-6-benzimidazole-pyrimidines.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H315,H319,H335
• P-Sätze: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves