540080

(S)-(+)-Epichlorhydrin

98%

• Synonym(e): (S)-(+)-2-(Chlormethyl)-oxiran
• Empirische Formel (Hill-System): C₃H₅ClO
• CAS-Nummer: 67843-74-7
• Molekulargewicht: 92.52
• Beilstein: 1420784
• MDL-Nummer: MFCD00077760
• UNSPSC-Code: 12352005
• PubChem Substanz-ID: 24878439
• NACRES: NA.22

Eigenschaften

• Dampfdichte: 3.2 (vs air)
• Qualitätsniveau: 200
• Dampfdruck: 12.5 mmHg ( 20 °C)
• Assay: 98%
• Optische Aktivität: [α]20/D +35°, c = 1 in methanol
• Optische Reinheit: ee: 97% (GLC)
• Selbstzündungstemp.: 1421 °F
• Expl.-Gr.: 21 %
• Brechungsindex: n20/D 1.438 (lit.)
• bp: 92-93 °C/360 mmHg (lit.)
• Dichte: 1.183 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: chloro; ether
• SMILES String: ClC[C@@H]1CO1
• InChI: 1S/C3H5ClO/c4-1-3-2-5-3/h3H,1-2H2/t3-/m1/s1
• InChIKey: BRLQWZUYTZBJKN-GSVOUGTGSA-N

Beschreibung

Anwendung

Chiral building block in the enantioselective syntheses of hydroxyisoxazolidines and (+)-cis-sylvaticin, a potential antitumor agent.

Used in the total synthesis of Macquarimicins and in the total synthesis of the macrolide RK-397.

Used to synthesize inhibitors of fatty acid oxidation as potential metabolic modulators.

Rechtliche Hinweise

Manufactured under license by Shasun Chemicals and Drugs Limited, using Jacobsen HKR technology.

Sicherheitshinweise

• Piktogramme: GHS02,GHS06,GHS08,GHS05
• Signalwort: Danger
• H-Sätze: H226,H301 + H311 + H331,H314,H317,H350
• P-Sätze: P202 - P210 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Eye Dam. 1 - Flam. Liq. 3 - Skin Corr. 1B - Skin Sens. 1
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 89.6 °F - closed cup
• Flammpunkt (°C): 32 °C - closed cup
• Persönliche Schutzausrüstung: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter