333115

2-Isopropylapfelsäure

98%

• Synonym(e): 2-Hydroxy-2-isopropyl-bernsteinsäure
• Lineare Formel: HO₂CCH₂C[CH(CH₃)₂](OH)CO₂H
• CAS-Nummer: 3237-44-3
• Molekulargewicht: 176.17
• NACRES: NA.22
• PubChem Substance ID: 24860103
• UNSPSC Code: 12352100
• MDL number: MFCD00075003
• Assay: 98%

Eigenschaften

• Quality Segment: 100
• assay: 98%
• mp: 144-146 °C (lit.)
• functional group: carboxylic acid, hydroxyl
• SMILES string: CC(C)C(O)(CC(O)=O)C(O)=O
• InChI: 1S/C7H12O5/c1-4(2)7(12,6(10)11)3-5(8)9/h4,12H,3H2,1-2H3,(H,8,9)(H,10,11)
• InChI key: BITYXLXUCSKTJS-UHFFFAOYSA-N

Beschreibung

General description

2-Isopropylmalic acid is an intermediate formed during leucine biosynthesis. Budding yeast Saccharomyces cerevisiae secrets 2-isopropylmalic acid and helps in reduction of aluminum toxicity by forming chelate with Al ions, thereby preventing them from entering the cells.

Application

2-Isopropylmalic acid was employed as an internal standard in diagnostic model for pancreatic cancer using GC/MS-based human serum metabolomics.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves