171859

Propiolsäure-methylester

99%

• Synonym(e): Acetylencarbonsäure-methylester
• Lineare Formel: HC≡CCO₂CH₃
• CAS-Nummer: 922-67-8
• Molekulargewicht: 84.07
• Beilstein: 605462
• EG-Nummer: 213-083-5
• MDL-Nummer: MFCD00008572
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 24850388
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 200
• Assay: 99%
• Form: liquid
• Brechungsindex: n20/D 1.408 (lit.)
• bp: 103-105 °C (lit.)
• Dichte: 0.945 g/mL at 25 °C (lit.)
• Funktionelle Gruppe: ester
• SMILES String: COC(=O)C#C
• InChI: 1S/C4H4O2/c1-3-4(5)6-2/h1H,2H3
• InChIKey: IMAKHNTVDGLIRY-UHFFFAOYSA-N

Beschreibung

Anwendung

N-3 protecting reagent for uridines and thymidines.

Used in a one-pot, four-component synthesis of 1,2,3,5-benzenetetracarboxylates promoted by Ph3P.

Methyl propiolate was used in the synthesis of polysubstituted 3-arylaminoacrylate and tetrahydropyrimidin-2-one derivatives. It was also used as a thiol derivatizing agent for capillary electrophoresis.

Sicherheitshinweise

• Piktogramme: GHS02,GHS07
• Signalwort: Danger
• H-Sätze: H225,H315,H319,H335
• P-Sätze: P210 - P233 - P240 - P241 - P303 + P361 + P353 - P305 + P351 + P338
• Gefahreneinstufungen: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 3 - Flammable liquids
• WGK: WGK 3
• Flammpunkt (°F): 60.8 °F - closed cup
• Flammpunkt (°C): 16 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter