14462

(−)-α-Bisabolol

≥93% (GC)

• Synonym(e): (−)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol, Levomenol
• Empirische Formel (Hill-System): C₁₅H₂₆O
• CAS-Nummer: 23089-26-1
• Molekulargewicht: 222.37
• EG-Nummer: 208-205-9
• MDL-Nummer: MFCD03412455
• UNSPSC-Code: 12352100
• PubChem Substanz-ID: 57647161
• NACRES: NA.22

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥93% (GC)
• Optische Aktivität: [α]/D -58±5°, neat
• Brechungsindex: n20/D 1.496
• Funktionelle Gruppe: hydroxyl
• SMILES String: C\C(C)=C\CC[C@](C)(O)[C@H]1CCC(C)=CC1
• InChI: 1S/C15H26O/c1-12(2)6-5-11-15(4,16)14-9-7-13(3)8-10-14/h6-7,14,16H,5,8-11H2,1-4H3/t14-,15+/m1/s1
• InChIKey: RGZSQWQPBWRIAQ-CABCVRRESA-N

Beschreibung

Allgemeine Beschreibung

(-)-α-Bisabolol is the major constituent of essential oil from leaves of Hymenocrater yazdianus.

Anwendung

(-)-α-Bisabolol was used to investigate the leishmanicidal and cytotoxic activity of essential oil of Vanillosmopsis arborea.

Biochem./physiol. Wirkung

α-Bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias. It is the inhibitor of voltage-dependent Ca(2+) channels in tracheal smooth muscle preparations of rat. It also inhibits human and rat glioma cell growth and survival. It is a potential new therapeutic agent against leishmaniasis.

Sicherheitshinweise

• H-Sätze: H412
• P-Sätze: P273 - P501
• Gefahreneinstufungen: Aquatic Chronic 3
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): 289.4 °F - closed cup
• Flammpunkt (°C): 143 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves