HPLC Analysis of Oxprenolol Enantiomers on Astec® Cellulose DMP
CONDITIONS
column
Astec Cellulose DMP, 25 cm x 4.6 mm I.D., 5 μm particles (51099AST)
mobile phase
[A] heptane; [B] isopropanol; [C] diethylamine; (80:20:0.1, A:B:C)
flow rate
1 mL/min
column temp.
30 °C
detector
UV, 254 nm
injection
15 μL
sample
oxprenolol, 1 g/L in 50:50 heptane:isopropanol
Description
Analysis Note
Oxprenolol enantiomers are resolved by normal phase chromatography.
Other Notes
Oxprenolol is a nonselective beta-blocker and is used to treat angina and hypertension.
Legal Information
Astec is a registered trademark of Merck KGaA, Darmstadt, Germany