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Key Documents

V900486

Sigma-Aldrich

Pancreatin from porcine pancreas

Vetec, reagent grade

Synonym(s):

Pancreatin from hog pancreas

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About This Item

CAS Number:
EC Number:
MDL number:
UNSPSC Code:
12352204

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grade

reagent grade

product line

Vetec

form

powder

storage temp.

−20°C

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This Item
CDS002953CDS013819
Quality Level

100

Quality Level

-

Quality Level

-

Biochem/physiol Actions

Pancreatin contains enzymatic components including trypsin, amylase and lipase, ribonuclease, and protease, produced by the exocrine cells of the porcine pancreas. This combination of enzymes allows it to hydrolyze proteins, starch and fats. Pancreatin will convert not less than 25 times its weight of potato starch into soluble carbohydrates in 5 minutes in water at 40°C, will digest not less than 25 times its weight of casein in 60 minutes at pH 7.5 at 40°C and will release not less than microequivalents of acid per min per mg pancreatin from olive oil at pH 9.0 at 37°C.

Legal Information

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Health hazardExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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    Mireille Andriamihaja et al.
    Amino acids, 44(2), 563-572 (2012-09-12)
    Utilisation of microbial enzymes may represent an alternative strategy to the use of conventional pancreatin obtained from pig pancreas for the treatment of severe pancreatic insufficiency. In this study, we focused on the capacity of two microbial preparations for their
    C M Seiler et al.
    Alimentary pharmacology & therapeutics, 37(7), 691-702 (2013-02-07)
    Pancreatic exocrine insufficiency (PEI) often occurs following pancreatic surgery. To demonstrate the superior efficacy of pancreatin 25 000 minimicrospheres (Creon 25000 MMS; 9-15 capsules/day) over placebo in treating PEI after pancreatic resection. A 1-week, double-blind, randomised, placebo-controlled, parallel-group, multicentre study with
    Zacharias Papanikolaou et al.
    Journal of food science, 77(5), M298-M306 (2012-11-21)
    Isolates (47) of lactobacilli from 5 different productions of Melichloro cheese were examined for potential use as adjunct cultures. The sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) of whole-cell proteins classified 29 isolates as L. paraplantarum and 18 as L. paracasei
    Xiao-Qiang Zou et al.
    Journal of agricultural and food chemistry, 60(37), 9415-9423 (2012-08-28)
    Human milk fat substitutes (HMFSs) were prepared by a two-step process, namely, Lipozyme RM IM-catalyzed acidolysis of interesterified high-melting palm stearin with fatty acids from rapeseed oil and blending of the enzymatic product with the selected oils on the basis
    Gema Pereira-Caro et al.
    International journal of food sciences and nutrition, 63(6), 703-707 (2012-01-25)
    The digestive stability of two natural antioxidant compounds present in virgin olive oil, hydroxytyrosol (HTy) and hydroxytyrosyl acetate (HTy-Ac) and a new series of hydroxytyrosyl ethers (methyl, ethyl and butyl hydroxytyrosyl ethers) was evaluated by a simulated digestion procedure. High

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