ADRA2A (α-2A adrenergic receptor gene) is located on human chromosome 10q25. It is expressed in the caudate nucleus.
Anti-Adrenergic Receptor α-2A Antibody detects endogenous levels of total Adrenergic Receptor α-2A protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human Adrenergic Receptor alpha-2A.
Immunogen Range: 331-380
Biochem/physiol Actions
ADRA2A (α-2A adrenergic receptor gene) plays an important role in irritability, impulsivity, aggression and memory traits. Mutations in ADRA2A affects the liberation of insulin and glucose regulation. Variations in ADRA2A is linked with poor clinical prognostication. It participates in autism spectrum disorders (ASDs).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Proceedings of the National Academy of Sciences of the United States of America, 112(13), E1659-E1668 (2015-03-17)
Recent evidence suggests that chemokine (C-X-C motif) receptor 4 (CXCR4) contributes to the regulation of blood pressure through interactions with α1-adrenergic receptors (ARs) in vascular smooth muscle. The underlying molecular mechanisms, however, are unknown. Using proximity ligation assays to visualize
Replication of genome-wide association studies (GWAS) loci for fasting plasma glucose in African-Americans
The noradrenergic system is proposed to play a prominent role in the pathogenesis of liver fibrosis. While α1- and β-adrenergic receptors (ARs) are suggested to be involved in a multitude of profibrogenic actions, little is known about α2-AR-mediated effects and
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